Somatostatin Analogs in the Medical Management of Occult Bleeding of the Lower Digestive Tract
Joint Authors
Martin-Grace, Julie
Tamagno, Gianluca
Source
Gastroenterology Research and Practice
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-09
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
The management of occult bleeding from the lower digestive tract can be very challenging.
In cases of identified angiodysplasia, the first line management options can be limited by a number of clinical or anatomical factors and an alternative approach might be required, including the use of medications.
Somatostatin analogs have been considered as an effective and well-tolerated alternative management option in a number of cases where the endoscopic therapeutic approach is not practical or is unsuccessful, in patients with coagulopathies or who need concomitant anticoagulation or antiplatelet treatment.
Despite the lack of double-blinded randomized placebo-control trials and despite the limitations of the available evidence in the literature, including small sample size, variable dosing, and administration routes, there is a consistent agreement in the literature that somatostatin analogs are a safe, well-tolerated, and effective therapeutic option for managing refractory or occult bleeding from the lower digestive tract, with particular reference to patients with angiodysplasia, where endoscopic or surgical management is either not feasible or unsuccessful and other pharmacological options are not preferred.
American Psychological Association (APA)
Martin-Grace, Julie& Tamagno, Gianluca. 2015. Somatostatin Analogs in the Medical Management of Occult Bleeding of the Lower Digestive Tract. Gastroenterology Research and Practice،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1064097
Modern Language Association (MLA)
Martin-Grace, Julie& Tamagno, Gianluca. Somatostatin Analogs in the Medical Management of Occult Bleeding of the Lower Digestive Tract. Gastroenterology Research and Practice No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1064097
American Medical Association (AMA)
Martin-Grace, Julie& Tamagno, Gianluca. Somatostatin Analogs in the Medical Management of Occult Bleeding of the Lower Digestive Tract. Gastroenterology Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1064097
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1064097