Association of Preoperative Biliary Drainage with Postoperative Morbidity after Pancreaticoduodenectomy
Joint Authors
Liu, Chang
Lu, Jian-Wen
Du, Zhao-Qing
Liu, Xue-Min
Lv, Yi
Zhang, Xu-Feng
Source
Gastroenterology Research and Practice
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-12-22
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
The advantages or disadvantages of preoperative biliary drainage (PBD) prior to pancreaticoduodenectomy (PD) remain unclear.
Methods.
A prospectively maintained database was queried for 335 consecutive patients undergoing standard PD surgery between 2009 and 2013.
Clinical data and postoperative complications of the 47 patients receiving PBD and 288 patients with early surgery were compared.
A matching analysis was also performed between patients receiving or not receiving PBD (no-PBD).
Results.
The indication for PBD was severe obstructive jaundice (81%) and cholangitis (26%) at the time of PBD.
47 PBD patients had higher bilirubin level than 288 no-PBD patients preoperatively (363.2 μ mol/L versus 136.0 μ mol/L, p < 0.001 ).
Although no significant difference of any complications could be observed between the two groups, positive intraoperative bile culture and wound infection seemed to be moderately increased in PBD compared to no-PBD patients ( p = 0.084 and 0.183, resp.).
In the matched-pair comparison, the incidence of wound infection was three times higher in PBD than no-PBD patients (14.9% versus 4.3%, p = 0.080 ).
Conclusions.
PBD seems to moderately increase the risk of postoperative wound and bile duct infection.
Therefore, PBD should be selectively performed prior to PD.
American Psychological Association (APA)
Liu, Chang& Lu, Jian-Wen& Du, Zhao-Qing& Liu, Xue-Min& Lv, Yi& Zhang, Xu-Feng. 2015. Association of Preoperative Biliary Drainage with Postoperative Morbidity after Pancreaticoduodenectomy. Gastroenterology Research and Practice،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1064120
Modern Language Association (MLA)
Liu, Chang…[et al.]. Association of Preoperative Biliary Drainage with Postoperative Morbidity after Pancreaticoduodenectomy. Gastroenterology Research and Practice No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1064120
American Medical Association (AMA)
Liu, Chang& Lu, Jian-Wen& Du, Zhao-Qing& Liu, Xue-Min& Lv, Yi& Zhang, Xu-Feng. Association of Preoperative Biliary Drainage with Postoperative Morbidity after Pancreaticoduodenectomy. Gastroenterology Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1064120
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1064120