Duodenal Aspirates for Small Intestine Bacterial Overgrowth: Yield, PPIs, and Outcomes after Treatment at a Tertiary Academic Medical Center
Joint Authors
Harrison, M. E.
Crowell, Michael D.
Kahn, Allon
Franco, Diana L.
Disbrow, Molly B.
Koepke, Laura M.
Ramirez, Francisco C.
Harris, Lucinda A.
Source
Gastroenterology Research and Practice
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-01-28
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Duodenal aspirates are not commonly collected, but they can be easily used in detection of small intestinal bacterial overgrowth (SIBO).
Proton pump inhibitor (PPI) use has been proposed to contribute to the development of SIBO.
We aimed to determine the yield of SIBO-positive cultures detected in duodenal aspirates, the relationship between SIBO and PPI use, and the clinical outcomes of patients identified by this method.
In a retrospective study, we analyzed electronic medical records from 1263 consecutive patients undergoing upper endoscopy at a tertiary medical center.
Aspirates were collected thought out the third and fourth portions of the duodenum, and cultures were considered to be positive for SIBO if they produced more than 100,000 cfu/mL.
Culture analysis of duodenal aspirates identified SIBO in one-third of patients.
A significantly higher percentage of patients with SIBO use PPIs than patients without SIBO, indicating a possible association.
Similar proportions of patients with SIBO improved whether or not they received antibiotic treatment, calling into question the use of this expensive therapy for this disorder.
American Psychological Association (APA)
Franco, Diana L.& Disbrow, Molly B.& Kahn, Allon& Koepke, Laura M.& Harris, Lucinda A.& Harrison, M. E.…[et al.]. 2015. Duodenal Aspirates for Small Intestine Bacterial Overgrowth: Yield, PPIs, and Outcomes after Treatment at a Tertiary Academic Medical Center. Gastroenterology Research and Practice،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1064367
Modern Language Association (MLA)
Franco, Diana L.…[et al.]. Duodenal Aspirates for Small Intestine Bacterial Overgrowth: Yield, PPIs, and Outcomes after Treatment at a Tertiary Academic Medical Center. Gastroenterology Research and Practice No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1064367
American Medical Association (AMA)
Franco, Diana L.& Disbrow, Molly B.& Kahn, Allon& Koepke, Laura M.& Harris, Lucinda A.& Harrison, M. E.…[et al.]. Duodenal Aspirates for Small Intestine Bacterial Overgrowth: Yield, PPIs, and Outcomes after Treatment at a Tertiary Academic Medical Center. Gastroenterology Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1064367
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1064367