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Green Synthesis of Silver Nanoparticles Using Extract of Oak Fruit Hull (Jaft): Synthesis and In Vitro Cytotoxic Effect on MCF-7 Cells
Joint Authors
Rashidipour, Marzieh
Heydari, Rouhollah
Source
International Journal of Breast Cancer
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-01-01
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
A green synthetic approach by using oak fruit hull (Jaft) extract for preparation of silver nanoparticles (AgNPs) was developed and optimized.
Parameters affecting the synthesis of AgNPs, such as temperature, extract pH, and concentration of extract (ratio of plant sample to extraction solvent), were investigated and optimized.
Optimum conditions for the synthesis of silver nanoparticles are as follows: Ag+ concentration, 1 mM; extract concentration, 40 g/L (4% w/v); pH = 9 and temperature, 45°C.
Biosynthesized silver nanoparticles were characterized using UV-visible absorption spectroscopy (UV-Vis), Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), dynamic light scattering (DLS), transmission electron microscopy (TEM), and scanning electron microscopy (SEM).
TEM and DLS analyses have shown the synthesized AgNPs were predominantly spherical in shape with an average size of 40 nm.
The cytotoxic activity of the synthesized AgNPs and Jaft extract containing AgNPs against human breast cancer cell (MCF-7) was investigated and the half maximal inhibitory concentrations (IC50) were found to be 50 and 0.04 μg/mL at 24 h incubation, respectively.
This eco-friendly and cost-effective synthesis method can be potentially used for large-scale production of silver nanoparticles.
American Psychological Association (APA)
Heydari, Rouhollah& Rashidipour, Marzieh. 2015. Green Synthesis of Silver Nanoparticles Using Extract of Oak Fruit Hull (Jaft): Synthesis and In Vitro Cytotoxic Effect on MCF-7 Cells. International Journal of Breast Cancer،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1065271
Modern Language Association (MLA)
Heydari, Rouhollah& Rashidipour, Marzieh. Green Synthesis of Silver Nanoparticles Using Extract of Oak Fruit Hull (Jaft): Synthesis and In Vitro Cytotoxic Effect on MCF-7 Cells. International Journal of Breast Cancer No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1065271
American Medical Association (AMA)
Heydari, Rouhollah& Rashidipour, Marzieh. Green Synthesis of Silver Nanoparticles Using Extract of Oak Fruit Hull (Jaft): Synthesis and In Vitro Cytotoxic Effect on MCF-7 Cells. International Journal of Breast Cancer. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1065271
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1065271