Histopathological, Histomorphometrical, and Radiographical Evaluation of Injectable Glass-Ceramic-Chitosan Nanocomposite in Bone Reconstruction of Rat
Joint Authors
Seyedmajidi, Maryam
Rabiee, Seyedmahmood
Haghanifar, Sina
Seyedmajidi, Seyedkamal
Jorsaraei, Seyed Gholam ali
Alaghehmand, Homayoun
Jamaatlu, Naghmeh
Bijani, Ali
Source
International Journal of Biomaterials
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-08
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
Bone defects following tumor resection and osteolysis due to bone lesions, periodontal tissue disorders, and bone reconstruction are challenges that surgeons face.
Gass-ceramic-chitosan nanocomposite contains chitosan, a derivative of crustaceans’ exoskeleton.
Methods.
Thirty-two 6–8-week-old male Wistar rats were chosen.
One hole on each right and left tibia was made.
The right tibia holes were filled with injectable glass-ceramic-chitosan nanocomposite, and the left tibia holes were left empty.
After 7, 14, 28, and 60 days, histopathological, histomorphometrical, and radiographical assessments were performed.
Results.
Radiographic density on days 7 and 14 was significantly higher in the right tibias than in the left tibias.
Trabecular bone thickness, which was higher in the right tibias, increased from day 7 to day 60 in both right and left tibias, although not significantly.
Conclusions.
Glass-ceramic-chitosan nanocomposite is suggested for use in bone repair in cases of bone loss.
More histopathological, histomorphometrical, and radiographical assessments are also recommended.
American Psychological Association (APA)
Seyedmajidi, Maryam& Rabiee, Seyedmahmood& Haghanifar, Sina& Seyedmajidi, Seyedkamal& Jorsaraei, Seyed Gholam ali& Alaghehmand, Homayoun…[et al.]. 2015. Histopathological, Histomorphometrical, and Radiographical Evaluation of Injectable Glass-Ceramic-Chitosan Nanocomposite in Bone Reconstruction of Rat. International Journal of Biomaterials،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1065302
Modern Language Association (MLA)
Seyedmajidi, Maryam…[et al.]. Histopathological, Histomorphometrical, and Radiographical Evaluation of Injectable Glass-Ceramic-Chitosan Nanocomposite in Bone Reconstruction of Rat. International Journal of Biomaterials No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1065302
American Medical Association (AMA)
Seyedmajidi, Maryam& Rabiee, Seyedmahmood& Haghanifar, Sina& Seyedmajidi, Seyedkamal& Jorsaraei, Seyed Gholam ali& Alaghehmand, Homayoun…[et al.]. Histopathological, Histomorphometrical, and Radiographical Evaluation of Injectable Glass-Ceramic-Chitosan Nanocomposite in Bone Reconstruction of Rat. International Journal of Biomaterials. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1065302
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1065302