Androgen Receptors Expression in Pituitary of Male Viscacha in relation to Growth and Reproductive Cycle
Joint Authors
Filippa, Verónica Palmira
Rosales, Gabriela Judith
Cruceño, Albana Andrea Marina
Mohamed, Fabian Heber
Source
International Journal of Endocrinology
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-07
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The aim of this work was to study the androgen receptors (AR) expression in pituitary pars distalis (PD) of male viscachas in relation to growth and reproductive cycle.
AR were detected by immunocytochemistry and quantified by image analysis.
Pituitary glands from fetus, immature, prepubertal, and adult viscachas during their reproductive cycle were used.
In the fetal PD, the immunoreactivity (ir) was mainly cytoplasmic.
In immature and prepubertal animals, AR-ir was cytoplasmic (ARc-ir) and nuclear (ARn-ir) in medial region.
In adult animals, ARn-ir cells were numerous at caudal end.
AR regionalization varied between the PD zones in relation to growth.
In immature animals, the ARn-ir increased whereas the cytoplasmic expression decreased in relation to the fetal glands.
The percentage of ARc-ir cells increased in prepubertal animals whereas the nuclear AR expression was predominant in adult viscachas.
The AR expression changed in adults, showing minimum percentage in the gonadal regression period.
The variation of nuclear AR expression was directly related with testosterone concentration.
These results demonstrated variations in the immunostaining pattern, regionalization, and number of AR-ir cells throughout development, growth, and reproductive cycle, suggesting the involvement of AR in the regulation of the pituitary activity of male viscacha.
American Psychological Association (APA)
Filippa, Verónica Palmira& Rosales, Gabriela Judith& Cruceño, Albana Andrea Marina& Mohamed, Fabian Heber. 2015. Androgen Receptors Expression in Pituitary of Male Viscacha in relation to Growth and Reproductive Cycle. International Journal of Endocrinology،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1065579
Modern Language Association (MLA)
Filippa, Verónica Palmira…[et al.]. Androgen Receptors Expression in Pituitary of Male Viscacha in relation to Growth and Reproductive Cycle. International Journal of Endocrinology No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1065579
American Medical Association (AMA)
Filippa, Verónica Palmira& Rosales, Gabriela Judith& Cruceño, Albana Andrea Marina& Mohamed, Fabian Heber. Androgen Receptors Expression in Pituitary of Male Viscacha in relation to Growth and Reproductive Cycle. International Journal of Endocrinology. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1065579
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1065579