Geographic-Related Differences of Pituitary Adenomas Hormone Profile: Analysis of Two Groups Coming from Southeastern and Eastern Europe
Joint Authors
Cimpean, Anca Maria
Melnic, Eugen
Bălinişteanu, Bogdan
Corlan, Ana
Coculescu, Mihail
Rusu, Sergiu
Raica, Marius
Source
International Journal of Endocrinology
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-11
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
We compared the immunoprofile of pituitary adenomas from Romania and Moldova.
One hundred and eighty cases coming from Romania (94 cases, group 1) and Moldova (86 cases, group 2) were assessed by immunohistochemistry regarding all six basic hormones expressed in pituitary adenomas.
Specific differences and similarities were found and stated for both groups.
In group 1, 70% of cases were pituitary adenomas positive for one hormone, 13% were plurihormonal, while 17% were negative.
In group 2, 50,3% of the cases expressed only one hormone and 12,5% were negative for all hormones.
The highest difference was observed for plurihormonal adenomas, found in about 37,2% of cases for group 2 (2.86 times higher for group 2 compared with group 1).
A higher incidence of GH-secreting adenomas characterized group “1,” while group “2” had the highest percent of LH-secreting adenomas, 55% of cases being positive.
Triple association was noticed in 4.25% of cases of group 1 and in 8,13% out of total cases, from group 2.
Four-hormone association was found only in group 2, noticed in 15,56% of the cases.
The present paper highlights strong evidences of a particular and different immunoprofile of pituitary adenomas coming from Romania and Moldova.
American Psychological Association (APA)
Cimpean, Anca Maria& Melnic, Eugen& Bălinişteanu, Bogdan& Corlan, Ana& Coculescu, Mihail& Rusu, Sergiu…[et al.]. 2015. Geographic-Related Differences of Pituitary Adenomas Hormone Profile: Analysis of Two Groups Coming from Southeastern and Eastern Europe. International Journal of Endocrinology،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1065584
Modern Language Association (MLA)
Cimpean, Anca Maria…[et al.]. Geographic-Related Differences of Pituitary Adenomas Hormone Profile: Analysis of Two Groups Coming from Southeastern and Eastern Europe. International Journal of Endocrinology No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1065584
American Medical Association (AMA)
Cimpean, Anca Maria& Melnic, Eugen& Bălinişteanu, Bogdan& Corlan, Ana& Coculescu, Mihail& Rusu, Sergiu…[et al.]. Geographic-Related Differences of Pituitary Adenomas Hormone Profile: Analysis of Two Groups Coming from Southeastern and Eastern Europe. International Journal of Endocrinology. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1065584
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1065584