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Influence of CAG Repeat Polymorphism on the Targets of Testosterone Action
Joint Authors
Tirabassi, Giacomo
Giorgio, Furlani
delli Muti, Nicola
Cignarelli, Angelo
Perrini, Sebastio
Gallo, Mariagrazia
Pallotti, Francesco
Paoli, Donatella
Lombardo, Francesco
Gandini, Loredana
Balercia, Giancarlo
Giorgino, F.
Lenzi, Andrea
Source
International Journal of Endocrinology
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-09-02
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
In the last decade, ample evidence has demonstrated the growing importance of androgen receptor (AR) CAG repeat polymorphism in andrology.
This genetic parameter is able to condition the peripheral effects of testosterone and therefore to influence male sexual function and fertility, cardiovascular risk, body composition, bone metabolism, the risk of prostate and testicular cancer, the psychiatric status, and the onset of neurodegenerative disorders.
In this review, we extensively discuss the literature data and identify a role for AR CAG repeat polymorphism in conditioning the systemic testosterone effects.
In particular, our main purpose was to provide an updated text able to shed light on the many and often contradictory findings reporting an influence of CAG repeat polymorphism on the targets of testosterone action.
American Psychological Association (APA)
Tirabassi, Giacomo& Cignarelli, Angelo& Perrini, Sebastio& delli Muti, Nicola& Giorgio, Furlani& Gallo, Mariagrazia…[et al.]. 2015. Influence of CAG Repeat Polymorphism on the Targets of Testosterone Action. International Journal of Endocrinology،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1065625
Modern Language Association (MLA)
Tirabassi, Giacomo…[et al.]. Influence of CAG Repeat Polymorphism on the Targets of Testosterone Action. International Journal of Endocrinology No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1065625
American Medical Association (AMA)
Tirabassi, Giacomo& Cignarelli, Angelo& Perrini, Sebastio& delli Muti, Nicola& Giorgio, Furlani& Gallo, Mariagrazia…[et al.]. Influence of CAG Repeat Polymorphism on the Targets of Testosterone Action. International Journal of Endocrinology. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1065625
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1065625