Elevated Systemic Neutrophil Count Is Associated with Diabetic Macroalbuminuria among Elderly Chinese
Joint Authors
Yang, Min
Liu, Jun
Xu, Jiong
Sun, Tiange
Sheng, Li
Chen, Zaoping
Wang, Fang
Huang, Xinmei
Wu, Yueyue
Mao, Jianfeng
Zhang, Rui
Source
International Journal of Endocrinology
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-12-30
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
This study investigated an association between systemic absolute neutrophil count (ANC) and albuminuria in elderly Chinese people.
Methods.
A cross-sectional study was conducted on 2265 participants attending a routine medical examination in Minhang District as part of a Platform of Chronic Disease program.
Their drug history, waist circumference, height, blood pressure, fasting blood glucose, ANC, and urine albumin levels were recorded.
This study conformed to the requirements of the STROBE statement.
Results.
Of the 2265 subjects, 1254 (55.4%) were diabetic and 641 (28.3%) had albuminuria.
The mean ANC of patients with diabetes comorbid with macroalbuminuria was significantly higher than that of both the nondiabetic patients and patients with diabetes with lower levels of albuminuria; the latter 2 groups had statistically similar ANC.
ANC significantly and positively correlated with levels of urine albumin.
Based on multivariate analysis, with each 109/L increase in ANC, the increase in rates of macroalbuminuria was significant but not in rates of albuminuria positivity.
Based on areas under the receiver operating characteristic curve, ANC was the strongest factor predicting macroalbuminuria.
Conclusions.
Elevated ANC was associated with macroalbuminuria in diabetes, indicating that neutrophil-mediated inflammation may be involved in the exacerbation of albuminuria.
American Psychological Association (APA)
Yang, Min& Liu, Jun& Xu, Jiong& Sun, Tiange& Sheng, Li& Chen, Zaoping…[et al.]. 2015. Elevated Systemic Neutrophil Count Is Associated with Diabetic Macroalbuminuria among Elderly Chinese. International Journal of Endocrinology،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1065652
Modern Language Association (MLA)
Yang, Min…[et al.]. Elevated Systemic Neutrophil Count Is Associated with Diabetic Macroalbuminuria among Elderly Chinese. International Journal of Endocrinology No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1065652
American Medical Association (AMA)
Yang, Min& Liu, Jun& Xu, Jiong& Sun, Tiange& Sheng, Li& Chen, Zaoping…[et al.]. Elevated Systemic Neutrophil Count Is Associated with Diabetic Macroalbuminuria among Elderly Chinese. International Journal of Endocrinology. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1065652
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1065652