Role of FTO in Adipocyte Development and Function: Recent Insights
Joint Authors
Merkestein, Myrte
Sellayah, Dyan
Source
International Journal of Endocrinology
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-12-16
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
In 2007, FTO was identified as the first genome-wide association study (GWAS) gene associated with obesity in humans.
Since then, various animal models have served to establish the mechanistic basis behind this association.
Many earlier studies focussed on FTO’s effects on food intake via central mechanisms.
Emerging evidence, however, implicates adipose tissue development and function in the causal relationship between perturbations in FTO expression and obesity.
The purpose of this mini review is to shed light on these new studies of FTO function in adipose tissue and present a clearer picture of its impact on obesity susceptibility.
American Psychological Association (APA)
Merkestein, Myrte& Sellayah, Dyan. 2015. Role of FTO in Adipocyte Development and Function: Recent Insights. International Journal of Endocrinology،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1065732
Modern Language Association (MLA)
Merkestein, Myrte& Sellayah, Dyan. Role of FTO in Adipocyte Development and Function: Recent Insights. International Journal of Endocrinology No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1065732
American Medical Association (AMA)
Merkestein, Myrte& Sellayah, Dyan. Role of FTO in Adipocyte Development and Function: Recent Insights. International Journal of Endocrinology. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1065732
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1065732