Thyroid Dysfunction and Associated Risk Factors among Nepalese Diabetes Mellitus Patients
Joint Authors
Khatiwada, Saroj
KC, Rajendra
Sah, Santosh Kumar
Khan, Seraj Ahmed
Chaudhari, Rajendra Kumar
Baral, Nirmal
Lamsal, Madhab
Source
International Journal of Endocrinology
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-09-07
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objectives.
To assess thyroid function and associated risk factors in Nepalese diabetes mellitus patients.
Methods.
A cross-sectional study was carried out among 419 diabetes mellitus patients at B.
P.
Koirala Institute of Health Sciences, Dharan, Nepal.
Information on demographic and anthropometric variables and risk factors for thyroid dysfunction was collected.
Blood samples were analysed to measure thyroid hormones, blood sugar, and lipid profile.
Results.
Prevalence rate of thyroid dysfunction was 36.03%, with subclinical hypothyroidism (26.5%) as the most common thyroid dysfunction.
Thyroid dysfunction was much common in females (42.85%) compared to males (30.04%) p=0.008 and in type 1 diabetes (50%) compared to type 2 diabetes mellitus (35.41%) p=0.218.
Diabetic patients with thyroid dysfunction had higher total cholesterol, HDL cholesterol, and LDL cholesterol in comparison to patients without thyroid dysfunction.
Significant risk factors for thyroid dysfunction, specifically hypothyroidism (overt and subclinical), were smoking (relative risk of 2.56 with 95% CI (1.99–3.29, p<0.001)), family history of thyroid disease (relative risk of 2.57 with 95% CI (2.0–3.31, p<0.001)), and female gender (relative risk of 1.44 with 95% CI (1.09–1.91, p=0.01)).
Conclusions.
Thyroid dysfunction is common among Nepalese diabetic patients.
Smoking, family history of thyroid disease, and female gender are significantly associated with thyroid dysfunction.
American Psychological Association (APA)
Khatiwada, Saroj& KC, Rajendra& Sah, Santosh Kumar& Khan, Seraj Ahmed& Chaudhari, Rajendra Kumar& Baral, Nirmal…[et al.]. 2015. Thyroid Dysfunction and Associated Risk Factors among Nepalese Diabetes Mellitus Patients. International Journal of Endocrinology،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1065746
Modern Language Association (MLA)
Khatiwada, Saroj…[et al.]. Thyroid Dysfunction and Associated Risk Factors among Nepalese Diabetes Mellitus Patients. International Journal of Endocrinology No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1065746
American Medical Association (AMA)
Khatiwada, Saroj& KC, Rajendra& Sah, Santosh Kumar& Khan, Seraj Ahmed& Chaudhari, Rajendra Kumar& Baral, Nirmal…[et al.]. Thyroid Dysfunction and Associated Risk Factors among Nepalese Diabetes Mellitus Patients. International Journal of Endocrinology. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1065746
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1065746