The Benefits and Risks of Prophylactic Central Neck Dissection for Papillary Thyroid Carcinoma: Prospective Cohort Study
Joint Authors
Oh, Kyoung Ho
Cho, Jae-Gu
Kwon, Soon-Young
Woo, Jeong-Soo
Baek, Seung-Kuk
Jung, Kwang-Yoon
Lee, Doh Young
Source
International Journal of Endocrinology
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-07-13
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objectives.
This study evaluated the benefits of performing prophylactic central neck dissection (CND) with total thyroidectomy (TT) in management of papillary thyroid carcinoma (PTC) patients who were clinically node-negative at presentation.
Methods.
A total of 257 patients with stage T1 or T2 PTC and without preoperative evidence of lymph node involvement (N0) were enrolled in this prospective study.
The patients were randomly assigned to two groups: (1) a total thyroidectomy (TT) group ( n = 104 ) or (2) a TT plus CND group ( n = 153 ).
The two groups were compared for their perioperative data, complication rates, disease recurrence rates, and clinical outcomes.
Results.
The two groups of patients were similar in age, sex ratio, follow-up duration, and tumor size ( P = 0.227 , 0.359, 0.214, and 0.878, resp.).
The two groups showed similar rates of disease recurrence (3.9% in the TT group versus 3.3% in the TT plus CND group); however, complications occurred more frequently in the TT plus CND group; especially transient hypocalcemia ( P = 0.043 ).
Conclusions.
Patients treated with TT plus CND had a higher rate of complications with similar recurrence rate.
We believe that CND may not be routinely recommended when treating patients with PTC.
American Psychological Association (APA)
Lee, Doh Young& Oh, Kyoung Ho& Cho, Jae-Gu& Kwon, Soon-Young& Woo, Jeong-Soo& Baek, Seung-Kuk…[et al.]. 2015. The Benefits and Risks of Prophylactic Central Neck Dissection for Papillary Thyroid Carcinoma: Prospective Cohort Study. International Journal of Endocrinology،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1065748
Modern Language Association (MLA)
Lee, Doh Young…[et al.]. The Benefits and Risks of Prophylactic Central Neck Dissection for Papillary Thyroid Carcinoma: Prospective Cohort Study. International Journal of Endocrinology No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1065748
American Medical Association (AMA)
Lee, Doh Young& Oh, Kyoung Ho& Cho, Jae-Gu& Kwon, Soon-Young& Woo, Jeong-Soo& Baek, Seung-Kuk…[et al.]. The Benefits and Risks of Prophylactic Central Neck Dissection for Papillary Thyroid Carcinoma: Prospective Cohort Study. International Journal of Endocrinology. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1065748
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1065748