Exocrine Pancreatic Insufficiency in Diabetic Patients: Prevalence, Mechanisms, and Treatment
Joint Authors
Delle Fave, Martina
Piciucchi, Matteo
Capurso, Gabriele
Archibugi, Livia
Capasso, Marina
Delle Fave, Gianfranco
Source
International Journal of Endocrinology
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-29
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Pancreas is a doubled-entity organ, with both an exocrine and an endocrine component, reciprocally interacting in a composed system whose function is relevant for digestion, absorption, and homeostasis of nutrients.
Thus, it is not surprising that disorders of the exocrine pancreas also affect the endocrine system and vice versa.
It is well-known that patients with chronic pancreatitis develop a peculiar form of diabetes (type III), caused by destruction and fibrotic injury of islet cells.
However, less is known on the influence of diabetes on pancreatic exocrine function.
Pancreatic exocrine insufficiency (PEI) has been reported to be common in diabetics, with a prevalence widely ranging, in different studies, in both type I (25–74%) and type II (28–54%) diabetes.
A long disease duration, high insulin requirement, and poor glycemic control seem to be risk factors for PEI occurrence.
The impact of pancreatic exocrine replacement therapy on glycemic, insulin, and incretins profiles has not been fully elucidated.
The present paper is aimed at reviewing published studies investigating the prevalence of PEI in diabetic patients and factors associated with its occurrence.
American Psychological Association (APA)
Piciucchi, Matteo& Capurso, Gabriele& Archibugi, Livia& Delle Fave, Martina& Capasso, Marina& Delle Fave, Gianfranco. 2015. Exocrine Pancreatic Insufficiency in Diabetic Patients: Prevalence, Mechanisms, and Treatment. International Journal of Endocrinology،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1065757
Modern Language Association (MLA)
Piciucchi, Matteo…[et al.]. Exocrine Pancreatic Insufficiency in Diabetic Patients: Prevalence, Mechanisms, and Treatment. International Journal of Endocrinology No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1065757
American Medical Association (AMA)
Piciucchi, Matteo& Capurso, Gabriele& Archibugi, Livia& Delle Fave, Martina& Capasso, Marina& Delle Fave, Gianfranco. Exocrine Pancreatic Insufficiency in Diabetic Patients: Prevalence, Mechanisms, and Treatment. International Journal of Endocrinology. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1065757
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1065757