Polycystic Ovary Syndrome: Important Underrecognised Cardiometabolic Risk Factor in Reproductive-Age Women
Joint Authors
Baldani, Dinka Pavicic
Skrgatic, Lana
Ougouag, Roya
Source
International Journal of Endocrinology
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-01
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder amongst women of reproductive age.
Although PCOS is diagnosed exclusively based on reproductive criteria, it is also a metabolic disorder.
Insulin resistance, impaired glucose tolerance, type 2 diabetes mellitus, obesity, and dyslipidemia are more common in women with PCOS than in age-comparable women without PCOS.
Many of the metabolic abnormalities that manifest in PCOS are worsened by the concurrent incidence of obesity.
However, some of these metabolic perturbations occur even in lean women with PCOS and therefore are rightfully recognized as intrinsic to PCOS.
The intrinsic factors that produce these metabolic disturbances are reviewed in this paper.
The consequences of obesity and the other metabolic aberrations are also discussed.
The metabolic perturbations in PCOS patients lead to chronic low-grade inflammation and to cardiovascular impairments that heighten the risk of having cardiovascular disease.
Even though many studies have shown an elevation in surrogate biomarkers of cardiovascular disease in PCOS women, it is still not clear to what extent and magnitude the elevation precipitates more frequent and earlier events.
American Psychological Association (APA)
Baldani, Dinka Pavicic& Skrgatic, Lana& Ougouag, Roya. 2015. Polycystic Ovary Syndrome: Important Underrecognised Cardiometabolic Risk Factor in Reproductive-Age Women. International Journal of Endocrinology،Vol. 2015, no. 2015, pp.1-17.
https://search.emarefa.net/detail/BIM-1065812
Modern Language Association (MLA)
Baldani, Dinka Pavicic…[et al.]. Polycystic Ovary Syndrome: Important Underrecognised Cardiometabolic Risk Factor in Reproductive-Age Women. International Journal of Endocrinology No. 2015 (2015), pp.1-17.
https://search.emarefa.net/detail/BIM-1065812
American Medical Association (AMA)
Baldani, Dinka Pavicic& Skrgatic, Lana& Ougouag, Roya. Polycystic Ovary Syndrome: Important Underrecognised Cardiometabolic Risk Factor in Reproductive-Age Women. International Journal of Endocrinology. 2015. Vol. 2015, no. 2015, pp.1-17.
https://search.emarefa.net/detail/BIM-1065812
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1065812