The Lipid Parameters and Lipoprotein(a) Excess in Hashimoto Thyroiditis
Joint Authors
Source
International Journal of Endocrinology
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-03
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
The risk of atherosclerotic heart disease is increased in autoimmune thyroiditis, although the reason is not clear.
Lipoprotein(a) (Lp(a)) excess has been identified as a powerful predictor of premature atherosclerotic vascular diseases.
The aim of this study is to investigate the relationship between Lp(a) levels and thyroid hormones in Hashimoto patients.
Method.
154 premenopausal female Hashimoto patients (48 patients with overthypothyroid (OH), 50 patients with subclinical hypothyroid (SH), and 56 patients with euthyroid Hashimoto to (EH)) were enrolled in this study.
The control group consists of 50 age matched volunteers.
In every group, thyroid function tests and lipid parameters with Lp(a) were measured.
Lp(a) excess was defined as Lp(a) > 30 mg/dL.
Results.
Total-C, LDL-C, TG, and Lp(a) levels were increased in Hashimoto group.
Total-C, LDL-C, and TG levels were higher in SH group than in the control group.
Total-C and LDL-C levels were also higher in EH group compared to controls.
Lp(a) levels were similar in SH and EH groups with controls.
However, excess Lp(a) was more common in subclinical hypothyroid and euthyroid Hashimoto group than in the control group.
Conclusion.
The Total-C and LDL-C levels and excess Lp(a) were higher even in euthyroid Hashimoto patients.
Thyroid autoimmunity may have some effect on Lp(a) and lipid metabolism.
American Psychological Association (APA)
Yetkin, D. O.& Dogantekin, B.. 2015. The Lipid Parameters and Lipoprotein(a) Excess in Hashimoto Thyroiditis. International Journal of Endocrinology،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1065904
Modern Language Association (MLA)
Yetkin, D. O.& Dogantekin, B.. The Lipid Parameters and Lipoprotein(a) Excess in Hashimoto Thyroiditis. International Journal of Endocrinology No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1065904
American Medical Association (AMA)
Yetkin, D. O.& Dogantekin, B.. The Lipid Parameters and Lipoprotein(a) Excess in Hashimoto Thyroiditis. International Journal of Endocrinology. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1065904
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1065904