Determinants of Secondary Hyperparathyroidism in Bariatric Patients after Roux-en-Y Gastric Bypass or Sleeve Gastrectomy: A Pilot Study
Joint Authors
Alexandrou, Andreas
Diamantis, Theodoros
Tsoka, Evangelia
Armeni, Eleni
Rizos, Demetrios
Panoulis, Constantinos
Liakakos, Theodoros
Lambrinoudaki, Irene
Augoulea, Areti
Source
International Journal of Endocrinology
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-09
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objective.
Nutritional deficiencies are common after bariatric surgery.
We aimed to assess the prevalence and possible predictors of secondary hyperparathyroidism (SHPT) in bariatric patients.
Methods.
A total of 95 patients who had undergone Roux-en-Y gastric bypass (RYGB) or sleeve gastrectomy (SG) were assessed after a median of 3 years after surgery.
Anthropometric/demographic and weight-loss parameters were compared according to the presence of SHPT, independently for men/premenopausal women and postmenopausal women.
Results.
SHPT was highly prevalent (men/premenopausal women, 52.1%; postmenopausal women, 31.9%).
Among men/premenopausal women, multivariate analysis indicated that SHPT was predicted by (a) 25-hydroxyvitamin D levels (Exp(B) = 0.869, P-value = 0.037), independently of age, sex, smoking; (b) calcium (Exp(B) = 0.159, P-value = 0.033) and smoking, independently of age and sex; (c) magnesium (Exp(B) = 0.026, P-value = 0.046) and smoking, independently of age and sex.
Among postmenopausal women, SHPT was predicted by menopausal age independently of age, smoking, and levels of 25-hydroxyvitamin D or calcium.
The development of SHPT was not associated with the type of surgery.
Conclusions.
RYGB and SG exhibited similar effects regarding the regulation of the hypothalamus-pituitary-parathyroid axis after surgery.
Vitamin D status and menopausal age appear to determine SHPT on the long term.
SHPT should be sought and vigorously treated with calcium and vitamin D supplementation.
American Psychological Association (APA)
Alexandrou, Andreas& Tsoka, Evangelia& Armeni, Eleni& Rizos, Demetrios& Diamantis, Theodoros& Augoulea, Areti…[et al.]. 2015. Determinants of Secondary Hyperparathyroidism in Bariatric Patients after Roux-en-Y Gastric Bypass or Sleeve Gastrectomy: A Pilot Study. International Journal of Endocrinology،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1065916
Modern Language Association (MLA)
Alexandrou, Andreas…[et al.]. Determinants of Secondary Hyperparathyroidism in Bariatric Patients after Roux-en-Y Gastric Bypass or Sleeve Gastrectomy: A Pilot Study. International Journal of Endocrinology No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1065916
American Medical Association (AMA)
Alexandrou, Andreas& Tsoka, Evangelia& Armeni, Eleni& Rizos, Demetrios& Diamantis, Theodoros& Augoulea, Areti…[et al.]. Determinants of Secondary Hyperparathyroidism in Bariatric Patients after Roux-en-Y Gastric Bypass or Sleeve Gastrectomy: A Pilot Study. International Journal of Endocrinology. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1065916
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1065916