An Omics Perspective on Molecular Biomarkers for Diagnosis, Prognosis, and Therapeutics of Cholangiocarcinoma
Joint Authors
Janvilisri, Tavan
Seeree, Pattaya
Pearngam, Phorutai
Kumkate, Supeecha
Source
International Journal of Genomics
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-09-02
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Cholangiocarcinoma (CCA) is an aggressive biliary tract malignancy arising from the epithelial bile duct.
The lack of early diagnostic biomarkers as well as therapeutic measures results in severe outcomes and poor prognosis.
Thus, effective early diagnostic, prognostic, and therapeutic biomarkers are required to improve the prognosis and prolong survival rates in CCA patients.
Recent advancement in omics technologies combined with the integrative experimental and clinical validations has provided an insight into the underlying mechanism of CCA initiation and progression as well as clues towards novel biomarkers.
This work highlights the discovery and validation of molecular markers in CCA identified through omics approaches.
The possible roles of these molecules in various cellular pathways, which render CCA carcinogenesis and progression, will also be discussed.
This paper can serve as a reference point for further investigations to yield deeper understanding in the complex feature of this disease, potentially leading to better approaches for diagnosis, prognosis, and therapeutics.
American Psychological Association (APA)
Seeree, Pattaya& Pearngam, Phorutai& Kumkate, Supeecha& Janvilisri, Tavan. 2015. An Omics Perspective on Molecular Biomarkers for Diagnosis, Prognosis, and Therapeutics of Cholangiocarcinoma. International Journal of Genomics،Vol. 2015, no. 2015, pp.1-16.
https://search.emarefa.net/detail/BIM-1065993
Modern Language Association (MLA)
Seeree, Pattaya…[et al.]. An Omics Perspective on Molecular Biomarkers for Diagnosis, Prognosis, and Therapeutics of Cholangiocarcinoma. International Journal of Genomics No. 2015 (2015), pp.1-16.
https://search.emarefa.net/detail/BIM-1065993
American Medical Association (AMA)
Seeree, Pattaya& Pearngam, Phorutai& Kumkate, Supeecha& Janvilisri, Tavan. An Omics Perspective on Molecular Biomarkers for Diagnosis, Prognosis, and Therapeutics of Cholangiocarcinoma. International Journal of Genomics. 2015. Vol. 2015, no. 2015, pp.1-16.
https://search.emarefa.net/detail/BIM-1065993
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1065993