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Genetics of Human and Canine Dilated Cardiomyopathy
Joint Authors
Simpson, Siobhan
Edwards, Jennifer
Ferguson-Mignan, Thomas F. N.
Cobb, Malcolm
Mongan, Nigel P.
Rutland, Catrin S.
Source
International Journal of Genomics
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-07-22
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Cardiovascular disease is a leading cause of death in both humans and dogs.
Dilated cardiomyopathy (DCM) accounts for a large number of these cases, reported to be the third most common form of cardiac disease in humans and the second most common in dogs.
In human studies of DCM there are more than 50 genetic loci associated with the disease.
Despite canine DCM having similar disease progression to human DCM studies into the genetic basis of canine DCM lag far behind those of human DCM.
In this review the aetiology, epidemiology, and clinical characteristics of canine DCM are examined, along with highlighting possible different subtypes of canine DCM and their potential relevance to human DCM.
Finally the current position of genetic research into canine and human DCM, including the genetic loci, is identified and the reasons many studies may have failed to find a genetic association with canine DCM are reviewed.
American Psychological Association (APA)
Simpson, Siobhan& Edwards, Jennifer& Ferguson-Mignan, Thomas F. N.& Cobb, Malcolm& Mongan, Nigel P.& Rutland, Catrin S.. 2015. Genetics of Human and Canine Dilated Cardiomyopathy. International Journal of Genomics،Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1065998
Modern Language Association (MLA)
Simpson, Siobhan…[et al.]. Genetics of Human and Canine Dilated Cardiomyopathy. International Journal of Genomics No. 2015 (2015), pp.1-13.
https://search.emarefa.net/detail/BIM-1065998
American Medical Association (AMA)
Simpson, Siobhan& Edwards, Jennifer& Ferguson-Mignan, Thomas F. N.& Cobb, Malcolm& Mongan, Nigel P.& Rutland, Catrin S.. Genetics of Human and Canine Dilated Cardiomyopathy. International Journal of Genomics. 2015. Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1065998
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1065998