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Comparative Genomics Revealed Genetic Diversity and SpeciesStrain-Level Differences in Carbohydrate Metabolism of Three Probiotic Bifidobacterial Species
Joint Authors
Odamaki, Toshitaka
Horigome, Ayako
Sugahara, Hirosuke
Hashikura, Nanami
Minami, Junichi
Xiao, Jin-zhong
Abe, Fumiaki
Source
International Journal of Genomics
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-07-05
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Strains of Bifidobacterium longum, Bifidobacterium breve, and Bifidobacterium animalis are widely used as probiotics in the food industry.
Although numerous studies have revealed the properties and functionality of these strains, it is uncertain whether these characteristics are species common or strain specific.
To address this issue, we performed a comparative genomic analysis of 49 strains belonging to these three bifidobacterial species to describe their genetic diversity and to evaluate species-level differences.
There were 166 common clusters between strains of B.
breve and B.
longum, whereas there were nine common clusters between strains of B.
animalis and B.
longum and four common clusters between strains of B.
animalis and B.
breve.
Further analysis focused on carbohydrate metabolism revealed the existence of certain strain-dependent genes, such as those encoding enzymes for host glycan utilisation or certain membrane transporters, and many genes commonly distributed at the species level, as was previously reported in studies with limited strains.
As B.
longum and B.
breve are human-residential bifidobacteria (HRB), whereas B.
animalis is a non-HRB species, several of the differences in these species’ gene distributions might be the result of their adaptations to the nutrient environment.
This information may aid both in selecting probiotic candidates and in understanding their potential function as probiotics.
American Psychological Association (APA)
Odamaki, Toshitaka& Horigome, Ayako& Sugahara, Hirosuke& Hashikura, Nanami& Minami, Junichi& Xiao, Jin-zhong…[et al.]. 2015. Comparative Genomics Revealed Genetic Diversity and SpeciesStrain-Level Differences in Carbohydrate Metabolism of Three Probiotic Bifidobacterial Species. International Journal of Genomics،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1066028
Modern Language Association (MLA)
Odamaki, Toshitaka…[et al.]. Comparative Genomics Revealed Genetic Diversity and SpeciesStrain-Level Differences in Carbohydrate Metabolism of Three Probiotic Bifidobacterial Species. International Journal of Genomics No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1066028
American Medical Association (AMA)
Odamaki, Toshitaka& Horigome, Ayako& Sugahara, Hirosuke& Hashikura, Nanami& Minami, Junichi& Xiao, Jin-zhong…[et al.]. Comparative Genomics Revealed Genetic Diversity and SpeciesStrain-Level Differences in Carbohydrate Metabolism of Three Probiotic Bifidobacterial Species. International Journal of Genomics. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1066028
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1066028