Factors That Could Impact on Liver Fibrosis Staging by Transient Elastography
Joint Authors
Perazzo, Hugo
Veloso, Valdilea G.
Grinsztejn, Beatriz
Hyde, Chris
Castro, Rodolfo
Source
International Journal of Hepatology
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-12-06
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Transient elastography (TE) based on liver stiffness measurement (LSM) is one of the most validated noninvasive methods for liver fibrosis staging in patients with chronic liver diseases.
This method is painless, has no potential complications, is rapid (<10 min), and can be performed at the patient’s bedside.
However, several points should be considered when interpreting TE results.
This review aims to discuss the critical points that might influence liver stiffness and TE results.
Spectrum bias and the impact of the prevalence of fibrosis stages should be taken into account when interpreting the studies that validated this method using liver biopsy as a gold-standard.
LSM might be influenced by nonfasting status, flare of transaminases, heart failure, extrahepatic cholestasis, presence of steatosis, aetiology of liver disease, type and position of probe, and operator’s experience.
In addition, interobserver variability can impact on the management of patients with chronic liver diseases.
TE should be performed by an experienced operator (>100 exams), in a 3-hour fasting status, and its results should be handled by specialist clinicians that are aware of the limitations of this method.
American Psychological Association (APA)
Perazzo, Hugo& Veloso, Valdilea G.& Grinsztejn, Beatriz& Hyde, Chris& Castro, Rodolfo. 2015. Factors That Could Impact on Liver Fibrosis Staging by Transient Elastography. International Journal of Hepatology،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1066075
Modern Language Association (MLA)
Perazzo, Hugo…[et al.]. Factors That Could Impact on Liver Fibrosis Staging by Transient Elastography. International Journal of Hepatology No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1066075
American Medical Association (AMA)
Perazzo, Hugo& Veloso, Valdilea G.& Grinsztejn, Beatriz& Hyde, Chris& Castro, Rodolfo. Factors That Could Impact on Liver Fibrosis Staging by Transient Elastography. International Journal of Hepatology. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1066075
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1066075