Liver Fibrosis and Mechanisms of the Protective Action of Medicinal Plants Targeting Inflammation and the Immune Response
Joint Authors
Cruz-Vega, Delia Elva
Duval, Florent
Maldonado-Bernal, Carmen
González-Garza, Maria Teresa
Moreno-Cuevas, Jorge E.
Source
International Journal of Inflammation
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-14
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Inflammation is a central feature of liver fibrosis as suggested by its role in the activation of hepatic stellate cells leading to extracellular matrix deposition.
During liver injury, inflammatory cells are recruited in the injurious site through chemokines attraction.
Thus, inflammation could be a target to reduce liver fibrosis.
The pandemic trend of obesity, combined with the high incidence of alcohol intake and viral hepatitis infections, highlights the urgent need to find accessible antifibrotic therapies.
Medicinal plants are achieving popularity as antifibrotic agents, supported by their safety, cost-effectiveness, and versatility.
The aim of this review is to describe the role of inflammation and the immune response in the pathogenesis of liver fibrosis and detail the mechanisms of inhibition of both events by medicinal plants in order to reduce liver fibrosis.
American Psychological Association (APA)
Duval, Florent& Moreno-Cuevas, Jorge E.& González-Garza, Maria Teresa& Maldonado-Bernal, Carmen& Cruz-Vega, Delia Elva. 2015. Liver Fibrosis and Mechanisms of the Protective Action of Medicinal Plants Targeting Inflammation and the Immune Response. International Journal of Inflammation،Vol. 2015, no. 2015, pp.1-14.
https://search.emarefa.net/detail/BIM-1066152
Modern Language Association (MLA)
Duval, Florent…[et al.]. Liver Fibrosis and Mechanisms of the Protective Action of Medicinal Plants Targeting Inflammation and the Immune Response. International Journal of Inflammation No. 2015 (2015), pp.1-14.
https://search.emarefa.net/detail/BIM-1066152
American Medical Association (AMA)
Duval, Florent& Moreno-Cuevas, Jorge E.& González-Garza, Maria Teresa& Maldonado-Bernal, Carmen& Cruz-Vega, Delia Elva. Liver Fibrosis and Mechanisms of the Protective Action of Medicinal Plants Targeting Inflammation and the Immune Response. International Journal of Inflammation. 2015. Vol. 2015, no. 2015, pp.1-14.
https://search.emarefa.net/detail/BIM-1066152
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1066152