Carbon Sources for Yeast Growth as a Precondition of Hydrogen Peroxide Induced Hormetic Phenotype

Abstract EN

Hormesis is a phenomenon of particular interest in biology, medicine, pharmacology, and toxicology.

In this study, we investigated the relationship between H2O2-induced hormetic response in S.

cerevisiae and carbon sources in yeast growth medium.

In general, our data indicate that (i) hydrogen peroxide induces hormesis in a concentration-dependent manner; (ii) the effect of hydrogen peroxide on yeast reproductive ability depends on the type of carbon substrate in growth medium; and (iii) metabolic and growth rates as well as catalase activity play an important role in H2O2-induced hormetic response in yeast.