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Preparation and Bioactivity Properties of a Novel Composite Membrane of Fructose Mediated β-Tricalcium Pyrophosphate(Polyethylene GlycolChitosan) for Guided Tissue Regeneration
Joint Authors
Wang, Jian-Wen
Kuo, Yi-Ming
Hon, Min-Hsiung
Chung, Mei-Hui
Source
International Journal of Polymer Science
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-11-01
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
A novel composite membrane of β-tricalcium pyrophosphate (β-TCP) and fructose- (F-) mediated chitosan/poly(ethylene glycol) (CS/PEG) was prepared by thermally induced phase separation technique.
The prepared composite membranes were characterized using scanning electron microscopy (SEM) and X-ray diffraction (XRD).
The mechanical property, swelling, degradation, and cytotoxicity of the composite membranes were evaluated in vitro with respect to its potential for use as biodegradable guided tissue regeneration (GTR) membrane.
In vitro degradation tests showed the composite membrane with a controllable degradation rate when changing the β-TCP content.
The incorporation of β-TCP granules also caused a significant enhancement of tensile strength.
When β-TCP content is controlled to 50 wt%, homogeneous composite membranes with well mechanical property and enzymatic degradation rate can be obtained.
Cytotoxicity assay demonstrates that the composite membranes were nontoxic and had very good cell compatibility.
Most importantly, the release of calcium ions and glucosamine from the composite membranes was proved to increase the cell proliferation of NIH3T3.
The results of this study have indicated that this novel F-β-TCP/CS/PEG composite can be a suitable material for GTR applications.
American Psychological Association (APA)
Wang, Jian-Wen& Hon, Min-Hsiung& Kuo, Yi-Ming& Chung, Mei-Hui. 2015. Preparation and Bioactivity Properties of a Novel Composite Membrane of Fructose Mediated β-Tricalcium Pyrophosphate(Polyethylene GlycolChitosan) for Guided Tissue Regeneration. International Journal of Polymer Science،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1066787
Modern Language Association (MLA)
Wang, Jian-Wen…[et al.]. Preparation and Bioactivity Properties of a Novel Composite Membrane of Fructose Mediated β-Tricalcium Pyrophosphate(Polyethylene GlycolChitosan) for Guided Tissue Regeneration. International Journal of Polymer Science No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1066787
American Medical Association (AMA)
Wang, Jian-Wen& Hon, Min-Hsiung& Kuo, Yi-Ming& Chung, Mei-Hui. Preparation and Bioactivity Properties of a Novel Composite Membrane of Fructose Mediated β-Tricalcium Pyrophosphate(Polyethylene GlycolChitosan) for Guided Tissue Regeneration. International Journal of Polymer Science. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1066787
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1066787