Preparation and Characterization of Urushiol Methylene Acetal Derivatives with Various Degrees of Unsaturation in Alkyl Side Chain
Joint Authors
Wang, Cheng-zhang
Zhou, Hao
He, Yuanfeng
Tao, Ran
Chen, Hongxia
Ye, Jianzhong
Zhang, Yusi
Source
International Journal of Polymer Science
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-27
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Preparation of urushiol derivatives was carried out in response to the drug industry’s increasing demand for new synthetic anticancer agents.
Urushiol methylene acetal derivatives were synthesized in high yields by reaction of urushiol with methylene chloride under the catalytic action of NaOH.
Four kinds of urushiol methylene acetal monomers were separated by silica-gel column and preparative HPLC, and their structures were elucidated by extensive spectroscopic methods, including 1D-NMR and 2D-NMR (1H, 13C-NMR, 1H-1HCOSY, HSQC, and HMBC) as well as TOF-MS.
They were identified as 3-[pentadecyl] benzene methylene ether (compound 1), 3-[8′-pentadecatrienyl] benzene methylene ether (compound 2), 3-[8′,11′-pentadecatrienyl] benzene methylene ether (compound 3), and 3-[8′,11′,14′-pentadecatrienyl] benzene methylene ether (compound 4).
This research provides a theoretical reference for exploration of these interesting and potentially bioactive compounds.
American Psychological Association (APA)
Wang, Cheng-zhang& He, Yuanfeng& Zhou, Hao& Tao, Ran& Chen, Hongxia& Ye, Jianzhong…[et al.]. 2015. Preparation and Characterization of Urushiol Methylene Acetal Derivatives with Various Degrees of Unsaturation in Alkyl Side Chain. International Journal of Polymer Science،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1066848
Modern Language Association (MLA)
Wang, Cheng-zhang…[et al.]. Preparation and Characterization of Urushiol Methylene Acetal Derivatives with Various Degrees of Unsaturation in Alkyl Side Chain. International Journal of Polymer Science No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1066848
American Medical Association (AMA)
Wang, Cheng-zhang& He, Yuanfeng& Zhou, Hao& Tao, Ran& Chen, Hongxia& Ye, Jianzhong…[et al.]. Preparation and Characterization of Urushiol Methylene Acetal Derivatives with Various Degrees of Unsaturation in Alkyl Side Chain. International Journal of Polymer Science. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1066848
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1066848