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Evaluation of Ovarian Reserve with Anti-Müllerian Hormone in Familial Mediterranean Fever
Joint Authors
Karakuş, Savaş
Durmaz, Yunus
Yıldız, Çağlar
Aydın, Hüseyin
Cengiz, Ahmet Kıvanç
Güler, Duygu
Şahin, Ali
Source
International Journal of Rheumatology
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-12
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objective.
To investigate ovarian reserves in attack-free familial Mediterranean fever (AF-FMF) patients at the reproductive age by anti-Müllerian hormone (AMH), antral follicle count (AFC), ovarian volume, and hormonal parameters.
Methods.
Thirty-three AF-FMF patients aging 18–45 years and 34 healthy women were enrolled and FSH, LH, E2, PRL, and AMH levels were measured in the morning blood samples at 2nd–4th days of menstruation by ELISA.
Concomitant pelvic ultrasonography was performed to calculate AFC and ovarian volumes.
Results.
In FMF patient group, median AMH levels were statistically significantly lower in the M69V mutation positive group than in the negative ones (P=0.018).
There was no statistically significant difference in median AMH levels between E148Q mutation positive patients and the negative ones (P=0.920).
There was also no statistically significant difference in median AMH levels between M680I mutation positive patients and the negative ones (P=0.868).
No statistically significant difference was observed in median AMH levels between patients who had at least one mutation and those with no mutations (P=0.868).
We realized that there was no difference in comparisons between ovarian volumes, number of follicles, and AMH levels ovarian reserves when compared with FMF patients and healthy individuals.
Conclusions.
Ovarian reserves of FMF pateints were similar to those of healthy subjects according to AMH.
However, AMH levels were lower in FMF patients with M694V mutation.
American Psychological Association (APA)
Şahin, Ali& Karakuş, Savaş& Durmaz, Yunus& Yıldız, Çağlar& Aydın, Hüseyin& Cengiz, Ahmet Kıvanç…[et al.]. 2015. Evaluation of Ovarian Reserve with Anti-Müllerian Hormone in Familial Mediterranean Fever. International Journal of Rheumatology،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1066883
Modern Language Association (MLA)
Şahin, Ali…[et al.]. Evaluation of Ovarian Reserve with Anti-Müllerian Hormone in Familial Mediterranean Fever. International Journal of Rheumatology No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1066883
American Medical Association (AMA)
Şahin, Ali& Karakuş, Savaş& Durmaz, Yunus& Yıldız, Çağlar& Aydın, Hüseyin& Cengiz, Ahmet Kıvanç…[et al.]. Evaluation of Ovarian Reserve with Anti-Müllerian Hormone in Familial Mediterranean Fever. International Journal of Rheumatology. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1066883
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1066883