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Comparative Evaluation of the Impact of Subacute Exposure of Smokeless Tobacco and Tobacco Smoke on Rat Testis
Joint Authors
Aprioku, Jonah Sydney
Ugwu, Theresa Chioma
Source
International Journal of Reproductive Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-11-08
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
This study investigated the effects of 30-day exposure to tobacco smoke (TS), smokeless tobacco (ST), and nicotine on reproductive parameters and oxidative biomarkers in prepubertal and adult male rats.
Sperm motility was reduced by 77.5 and 89.0% in TS and ST exposed prepubertal rats and 71.1 and 86.4% in adult rats, respectively.
Sperm count was also reduced by 64.7 and 89.9% in prepubertal rats and 64.9 and 47.0% in adult rats, respectively.
Nicotine decreased sperm motility (82.2%) and count (62.6%) in prepubertal rats but caused no effect in adult rats.
There were no changes in sperm morphology; testosterone was decreased, while LH and FSH were increased in exposed rats, when compared with control.
Malondialdehyde levels in testes of exposed rats were increased, and GSH, SOD, and catalase were altered.
Results indicate that subacute exposure of tobacco products alters sperm characteristics in a rank order of ST > TS > nicotine, which may be linked to increase in oxidative stress in the testis.
American Psychological Association (APA)
Aprioku, Jonah Sydney& Ugwu, Theresa Chioma. 2015. Comparative Evaluation of the Impact of Subacute Exposure of Smokeless Tobacco and Tobacco Smoke on Rat Testis. International Journal of Reproductive Medicine،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1066956
Modern Language Association (MLA)
Aprioku, Jonah Sydney& Ugwu, Theresa Chioma. Comparative Evaluation of the Impact of Subacute Exposure of Smokeless Tobacco and Tobacco Smoke on Rat Testis. International Journal of Reproductive Medicine No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1066956
American Medical Association (AMA)
Aprioku, Jonah Sydney& Ugwu, Theresa Chioma. Comparative Evaluation of the Impact of Subacute Exposure of Smokeless Tobacco and Tobacco Smoke on Rat Testis. International Journal of Reproductive Medicine. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1066956
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1066956