Now, Later of Never: Multicenter Randomized Controlled Trial Call—Is Surgery Necessary after Atypical Breast Core Biopsy Results in Mammographic Screening Settings?
Author
Source
International Journal of Surgical Oncology
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-21
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Breast cancer mammographic screening leads to detection of premalignant and preinvasive lesions with an increasing frequency.
Nevertheless, current epidemiologic evidence indicates that the screening reduces breast cancer specific mortality, but not overall mortality in breast cancer patients.
The evidence is lacking whether aggressive eradication of DCIS (preinvasive form of breast carcinoma) by surgery and radiation is of survival benefit, as long-term breast cancer specific mortality in a cohort of patients with DCIS is already in a single digit percent range.
Furthermore, it is currently not known whether the aggressive surgical eradication of atypical breast lesions which fall short of diagnosis of DCIS is of any benefit for the patients.
Here we propose a model for a randomized controlled trial to generate high level evidence and solve this dilemma.
American Psychological Association (APA)
Makretsov, Nikita. 2015. Now, Later of Never: Multicenter Randomized Controlled Trial Call—Is Surgery Necessary after Atypical Breast Core Biopsy Results in Mammographic Screening Settings?. International Journal of Surgical Oncology،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1066962
Modern Language Association (MLA)
Makretsov, Nikita. Now, Later of Never: Multicenter Randomized Controlled Trial Call—Is Surgery Necessary after Atypical Breast Core Biopsy Results in Mammographic Screening Settings?. International Journal of Surgical Oncology No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1066962
American Medical Association (AMA)
Makretsov, Nikita. Now, Later of Never: Multicenter Randomized Controlled Trial Call—Is Surgery Necessary after Atypical Breast Core Biopsy Results in Mammographic Screening Settings?. International Journal of Surgical Oncology. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1066962
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1066962