Gastrectomy and D2 Lymphadenectomy for Gastric Cancer: A Meta-Analysis Comparing the Harmonic Scalpel to Conventional Techniques
Joint Authors
Cheng, Hang
Hsiao, Chia-Wen
Clymer, Jeffrey W.
Schwiers, Michael L.
Tibensky, Bryanna N.
Patel, Leena
Ferko, Nicole C.
Chekan, Edward
Source
International Journal of Surgical Oncology
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-14
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The ultrasonic Harmonic scalpel has demonstrated clinical and surgical benefits in dissection and coagulation.
To evaluate its use in gastrectomy, we conducted a systematic review and meta-analysis of randomized controlled trials comparing the Harmonic scalpel to conventional techniques in gastrectomy for patients with gastric cancer.
International databases were searched without language restrictions for comparisons in open or laparoscopic gastrectomy and lymphadenectomy.
The meta-analysis used a random-effects model for all outcomes; continuous variables were analyzed for mean differences and dichotomous variables were analyzed for risk ratios.
Sensitivity analyses were conducted for study quality, type of conventional technique, and imputation of study results.
Ten studies (N=935) met the inclusion criteria.
Compared with conventional hemostatic techniques, the Harmonic scalpel demonstrated significant reductions in operating time (−27.5 min; P<0.001), intraoperative blood loss (−93.2 mL; P<0.001), and drainage volume (−138.8 mL; P<0.001).
Results were numerically higher for conventional techniques for hospital length of stay, complication risk, and transfusions but did not reach statistical significance.
Results remained robust to sensitivity analyses.
This meta-analysis demonstrates the clear advantages of using the Harmonic scalpel compared to conventional techniques, with improvements demonstrated across several outcome measures for patients undergoing gastrectomy and lymphadenectomy.
American Psychological Association (APA)
Cheng, Hang& Hsiao, Chia-Wen& Clymer, Jeffrey W.& Schwiers, Michael L.& Tibensky, Bryanna N.& Patel, Leena…[et al.]. 2015. Gastrectomy and D2 Lymphadenectomy for Gastric Cancer: A Meta-Analysis Comparing the Harmonic Scalpel to Conventional Techniques. International Journal of Surgical Oncology،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1066964
Modern Language Association (MLA)
Cheng, Hang…[et al.]. Gastrectomy and D2 Lymphadenectomy for Gastric Cancer: A Meta-Analysis Comparing the Harmonic Scalpel to Conventional Techniques. International Journal of Surgical Oncology No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1066964
American Medical Association (AMA)
Cheng, Hang& Hsiao, Chia-Wen& Clymer, Jeffrey W.& Schwiers, Michael L.& Tibensky, Bryanna N.& Patel, Leena…[et al.]. Gastrectomy and D2 Lymphadenectomy for Gastric Cancer: A Meta-Analysis Comparing the Harmonic Scalpel to Conventional Techniques. International Journal of Surgical Oncology. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1066964
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1066964