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Side Effects of Chloroquine and Primaquine and Symptom Reduction in Malaria Endemic Area (Mâncio Lima, Acre, Brazil)
Joint Authors
Martins, Antonio Camargo
Filgueira Júnior, José Alcântara
Braga, Cássio Braga e
Cayotopa, Athaid David Escalante
Klein, Wagner Werner
Schlosser, Andreus Roberto
Silva, Aline Ferreira da
Souza, Mardelson Nery de
Andrade, Breno Wilson Benevides
Pinto, Wagner de Jesus
da Silva-Nunes, M.
Source
Interdisciplinary Perspectives on Infectious Diseases
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-18
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Side effects of antimalarial drug can overlap with malaria symptoms.
We evaluated 50 patients with vivax malaria in Mâncio Lima, Acre, treated with chloroquine and primaquine.
Patients were evaluated for the presence of 21 symptoms before and after treatment and for reported side effects of these drugs after treatment was started.
The most frequent symptoms before medication were headache, fever, chills, sweating, arthralgia, back pain, and weakness, which were present in between 40% and 76% of respondents.
The treatment reduced the occurrence of these symptoms and reduced the lack of appetite, but gastrointestinal symptoms and choluria increased in frequency.
There were no reports of pale stools before medication, but 12% reported the occurrence of this symptom after treatment started.
Other symptoms such as blurred vision (54%), pruritus (22%), paresthesia (6%), insomnia (46%), and “stings” into the skin (22%) were reported after chloroquine was taken.
The antimalarial drugs used to treat P.
vivax malaria reduce much of the systemic and algic symptoms but cause mainly gastrointestinal side effects that may lead to lack of adherence to drug treatment.
It is important to guide the patient for the appearance and the transience of such side effects in order to avoid abandoning treatment.
American Psychological Association (APA)
Braga, Cássio Braga e& Martins, Antonio Camargo& Cayotopa, Athaid David Escalante& Klein, Wagner Werner& Schlosser, Andreus Roberto& Silva, Aline Ferreira da…[et al.]. 2015. Side Effects of Chloroquine and Primaquine and Symptom Reduction in Malaria Endemic Area (Mâncio Lima, Acre, Brazil). Interdisciplinary Perspectives on Infectious Diseases،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1067003
Modern Language Association (MLA)
Braga, Cássio Braga e…[et al.]. Side Effects of Chloroquine and Primaquine and Symptom Reduction in Malaria Endemic Area (Mâncio Lima, Acre, Brazil). Interdisciplinary Perspectives on Infectious Diseases No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1067003
American Medical Association (AMA)
Braga, Cássio Braga e& Martins, Antonio Camargo& Cayotopa, Athaid David Escalante& Klein, Wagner Werner& Schlosser, Andreus Roberto& Silva, Aline Ferreira da…[et al.]. Side Effects of Chloroquine and Primaquine and Symptom Reduction in Malaria Endemic Area (Mâncio Lima, Acre, Brazil). Interdisciplinary Perspectives on Infectious Diseases. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1067003
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1067003