An On-Line Solid Phase Extraction-Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Perfluoroalkyl Acids in Drinking and Surface Waters
Joint Authors
Polesello, S.
Mazzoni, Michela
Rusconi, Marianna
Martins, Claudia P. B.
Valsecchi, S.
Source
Journal of Analytical Methods in Chemistry
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-05
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
An UHPLC-MS/MS multiresidue method based on an on-line solid phase extraction (SPE) procedure was developed for the simultaneous determination of 9 perfluorinated carboxylates (from 4 to 12 carbon atoms) and 3 perfluorinated sulphonates (from 4 to 8 carbon atoms).
This work proposes using an on-line solid phase extraction before chromatographic separation and analysis to replace traditional methods of off-line SPE before direct injection to LC-MS/MS.
Manual sample preparation was reduced to sample centrifugation and acidification, thus eliminating several procedural errors and significantly reducing time-consuming and costs.
Ionization suppression between target perfluorinated analytes and their coeluting SIL-IS were detected for homologues with a number of carbon atoms less than 9, but the quantitation was not affected.
Total matrix effect corrected by SIL-IS, inclusive of extraction efficacy, and of ionization efficiency, ranged between −34 and +39%.
The percentage of recoveries, between 76 and 134%, calculated in different matrices (tap water and rivers impacted by different pollutions) was generally satisfactory.
LODs and LOQs of this on-line SPE method, which also incorporate recovery losses, ranged from 0.2 to 5.0 ng/L and from 1 to 20 ng/L, respectively.
Validated on-line SPE-LC/MS/MS method has been applied in a wide survey for the determination of perfluoroalkyl acids in Italian surface and ground waters.
American Psychological Association (APA)
Mazzoni, Michela& Rusconi, Marianna& Valsecchi, S.& Martins, Claudia P. B.& Polesello, S.. 2015. An On-Line Solid Phase Extraction-Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Perfluoroalkyl Acids in Drinking and Surface Waters. Journal of Analytical Methods in Chemistry،Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1067253
Modern Language Association (MLA)
Mazzoni, Michela…[et al.]. An On-Line Solid Phase Extraction-Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Perfluoroalkyl Acids in Drinking and Surface Waters. Journal of Analytical Methods in Chemistry No. 2015 (2015), pp.1-13.
https://search.emarefa.net/detail/BIM-1067253
American Medical Association (AMA)
Mazzoni, Michela& Rusconi, Marianna& Valsecchi, S.& Martins, Claudia P. B.& Polesello, S.. An On-Line Solid Phase Extraction-Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Perfluoroalkyl Acids in Drinking and Surface Waters. Journal of Analytical Methods in Chemistry. 2015. Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1067253
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1067253