Biotransformation of Indole to 3-Methylindole by Lysinibacillus xylanilyticus Strain MA
Joint Authors
Arora, Pankaj Kumar
Dhar, Kartik
Veloz García, Rafael Alejandro
Sharma, Ashutosh
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-23
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
An indole-biotransforming strain MA was identified as Lysinibacillus xylanilyticus on the basis of the 16S rRNA gene sequencing.
It transforms indole completely from the broth culture in the presence of an additional carbon source (i.e., sodium succinate).
Gas-chromatography-mass spectrometry identified indole-3-acetamide, indole-3-acetic acid, and 3-methylindole as transformation products.
Tryptophan-2-monooxygenase activity was detected in the crude extracts of indole-induced cells of strain MA, which confirms the formation of indole-3-acetamide from tryptophan in the degradation pathway of indole.
On the basis of identified metabolites and enzyme assay, we have proposed a new transformation pathway for indole degradation.
Indole was first transformed to indole-3-acetamide via tryptophan.
Indole-3-acetamide was then transformed to indole-3-acetic acid that was decarboxylated to 3-methylindole.
This is the first report of a 3-methylindole synthesis via the degradation pathway of indole.
American Psychological Association (APA)
Arora, Pankaj Kumar& Dhar, Kartik& Veloz García, Rafael Alejandro& Sharma, Ashutosh. 2015. Biotransformation of Indole to 3-Methylindole by Lysinibacillus xylanilyticus Strain MA. Journal of Chemistry،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1067455
Modern Language Association (MLA)
Arora, Pankaj Kumar…[et al.]. Biotransformation of Indole to 3-Methylindole by Lysinibacillus xylanilyticus Strain MA. Journal of Chemistry No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1067455
American Medical Association (AMA)
Arora, Pankaj Kumar& Dhar, Kartik& Veloz García, Rafael Alejandro& Sharma, Ashutosh. Biotransformation of Indole to 3-Methylindole by Lysinibacillus xylanilyticus Strain MA. Journal of Chemistry. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1067455
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1067455