Serum Cystatin C, Markers of Chronic Kidney Disease, and Retinopathy in Persons with Diabetes
Joint Authors
Wong, Chee Wai
Lamoureux, Ecosse
Ikram, Mohammad Kamran
Tai, E. Shyong
Sethi, Sunil
Sabanayagam, Charumathi
Wang, Jie Jin
Wong, Tien Yin
Teo, Boon Wee
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-20
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Purpose.
We examined the association of CKD defined by serum creatinine, serum cystatin C, and albuminuria with moderate diabetic retinopathy (DR).
Methods.
We examined 1,119 Indian adults with diabetes, aged 40–80 years, who participated in the Singapore Indian Eye Study (2007–2009), a population-based cross-sectional study.
The associations of CKD defined by each of the three markers alone and in combination with moderate DR were examined using logistic regression models adjusted for potential confounding factors including duration of diabetes, smoking, body mass index, systolic blood pressure, and HbA1c.
Results.
The prevalence of moderate DR was significantly higher among those with CKD defined by triple markers (41.1%) compared to CKD defined separately by creatinine (26.6%), cystatin C (20.9%), and albuminuria (23.4%).
People with CKD defined by triple markers had a fourteenfold higher odds of moderate DR (OR (95% CI) = 13.63 (6.08–30.54)) compared to those without CKD by any marker.
Nearly half (48.7%) of participants with cystatin C ≥ 1.12 mg/L have moderate DR.
Conclusions.
CKD defined by a triple marker panel was strongly associated with moderate DR in this Asian population with diabetes.
American Psychological Association (APA)
Wong, Chee Wai& Teo, Boon Wee& Lamoureux, Ecosse& Ikram, Mohammad Kamran& Wang, Jie Jin& Tai, E. Shyong…[et al.]. 2015. Serum Cystatin C, Markers of Chronic Kidney Disease, and Retinopathy in Persons with Diabetes. Journal of Diabetes Research،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1067902
Modern Language Association (MLA)
Wong, Chee Wai…[et al.]. Serum Cystatin C, Markers of Chronic Kidney Disease, and Retinopathy in Persons with Diabetes. Journal of Diabetes Research No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1067902
American Medical Association (AMA)
Wong, Chee Wai& Teo, Boon Wee& Lamoureux, Ecosse& Ikram, Mohammad Kamran& Wang, Jie Jin& Tai, E. Shyong…[et al.]. Serum Cystatin C, Markers of Chronic Kidney Disease, and Retinopathy in Persons with Diabetes. Journal of Diabetes Research. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1067902
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1067902