A New Approach to Define and Diagnose Cardiometabolic Disorder in Children
Joint Authors
Lauersen, Jeppe Bo
Brønd, Jan Christian
Anderssen, Sigmund Alfred
Steene-Johannessen, Jostein
Barros, Mauro V. G.
Kriemler, Susi
Møller, Niels Christian
Kristensen, Peter Lund
Ried-Larsen, Mathias
Grøntved, Anders
Ekelund, Ulf
G. McMurray, Robert
Bugge, Anna
Andersen, Lars B.
Sardinha, Luís B.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-06
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The aim of the study was to test the performance of a new definition of metabolic syndrome (MetS), which better describes metabolic dysfunction in children.
Methods.
15,794 youths aged 6–18 years participated.
Mean z-score for CVD risk factors was calculated.
Sensitivity analyses were performed to evaluate which parameters best described the metabolic dysfunction by analysing the score against independent variables not included in the score.
Results.
More youth had clustering of CVD risk factors (>6.2%) compared to the number selected by existing MetS definitions (International Diabetes Federation (IDF) < 1%).
Waist circumference and BMI were interchangeable, but using insulin resistance homeostasis model assessment (HOMA) instead of fasting glucose increased the score.
The continuous MetS score was increased when cardiorespiratory fitness (CRF) and leptin were included.
A mean z-score of 0.40–0.85 indicated borderline and above 0.85 indicated clustering of risk factors.
A noninvasive risk score based on adiposity and CRF showed sensitivity and specificity of 0.85 and an area under the curve of 0.92 against IDF definition of MetS.
Conclusions.
Diagnosis for MetS in youth can be improved by using continuous variables for risk factors and by including CRF and leptin.
American Psychological Association (APA)
Andersen, Lars B.& Lauersen, Jeppe Bo& Brønd, Jan Christian& Anderssen, Sigmund Alfred& Sardinha, Luís B.& Steene-Johannessen, Jostein…[et al.]. 2015. A New Approach to Define and Diagnose Cardiometabolic Disorder in Children. Journal of Diabetes Research،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1067942
Modern Language Association (MLA)
Andersen, Lars B.…[et al.]. A New Approach to Define and Diagnose Cardiometabolic Disorder in Children. Journal of Diabetes Research No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1067942
American Medical Association (AMA)
Andersen, Lars B.& Lauersen, Jeppe Bo& Brønd, Jan Christian& Anderssen, Sigmund Alfred& Sardinha, Luís B.& Steene-Johannessen, Jostein…[et al.]. A New Approach to Define and Diagnose Cardiometabolic Disorder in Children. Journal of Diabetes Research. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1067942
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1067942