Diabetic Retinopathy: Vascular and Inflammatory Disease
Joint Authors
Romano, Mario R.
Semeraro, F.
Cancarini, A.
Rezzola, S.
dell'Omo, Roberto
Costagliola, Ciro
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-07
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Diabetic retinopathy (DR) is the leading cause of visual impairment in the working-age population of the Western world.
The pathogenesis of DR is complex and several vascular, inflammatory, and neuronal mechanisms are involved.
Inflammation mediates structural and molecular alterations associated with DR.
However, the molecular mechanisms underlying the inflammatory pathways associated with DR are not completely characterized.
Previous studies indicate that tissue hypoxia and dysregulation of immune responses associated with diabetes mellitus can induce increased expression of numerous vitreous mediators responsible for DR development.
Thus, analysis of vitreous humor obtained from diabetic patients has made it possible to identify some of the mediators (cytokines, chemokines, and other factors) responsible for DR pathogenesis.
Further studies are needed to better understand the relationship between inflammation and DR.
Herein the main vitreous-related factors triggering the occurrence of retinal complication in diabetes are highlighted.
American Psychological Association (APA)
Semeraro, F.& Cancarini, A.& dell'Omo, Roberto& Rezzola, S.& Romano, Mario R.& Costagliola, Ciro. 2015. Diabetic Retinopathy: Vascular and Inflammatory Disease. Journal of Diabetes Research،Vol. 2015, no. 2015, pp.1-16.
https://search.emarefa.net/detail/BIM-1067950
Modern Language Association (MLA)
Semeraro, F.…[et al.]. Diabetic Retinopathy: Vascular and Inflammatory Disease. Journal of Diabetes Research No. 2015 (2015), pp.1-16.
https://search.emarefa.net/detail/BIM-1067950
American Medical Association (AMA)
Semeraro, F.& Cancarini, A.& dell'Omo, Roberto& Rezzola, S.& Romano, Mario R.& Costagliola, Ciro. Diabetic Retinopathy: Vascular and Inflammatory Disease. Journal of Diabetes Research. 2015. Vol. 2015, no. 2015, pp.1-16.
https://search.emarefa.net/detail/BIM-1067950
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1067950