Present and Future in the Treatment of Diabetic Kidney Disease
Joint Authors
Quiroga, Borja
de Arriba, Gabriel
Arroyo, David
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-07
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Diabetic kidney disease is the leading cause of end-stage renal disease.
Albuminuria is recognized as the most important prognostic factor for chronic kidney disease progression.
For this reason, blockade of renin-angiotensin system remains the main recommended strategy, with either angiotensin converting enzyme inhibitors or angiotensin II receptor blockers.
However, other antiproteinuric treatments have begun to be studied, such as direct renin inhibitors or aldosterone blockers.
Beyond antiproteinuric treatments, other drugs such as pentoxifylline or bardoxolone have yielded conflicting results.
Finally, alternative pathogenic pathways are being explored, and emerging therapies including antifibrotic agents, endothelin receptor antagonists, or transcription factors show promising results.
The aim of this review is to explain the advances in newer agents to treat diabetic kidney disease, along with the background of the renin-angiotensin system blockade.
American Psychological Association (APA)
Quiroga, Borja& Arroyo, David& de Arriba, Gabriel. 2015. Present and Future in the Treatment of Diabetic Kidney Disease. Journal of Diabetes Research،Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1068004
Modern Language Association (MLA)
Quiroga, Borja…[et al.]. Present and Future in the Treatment of Diabetic Kidney Disease. Journal of Diabetes Research No. 2015 (2015), pp.1-13.
https://search.emarefa.net/detail/BIM-1068004
American Medical Association (AMA)
Quiroga, Borja& Arroyo, David& de Arriba, Gabriel. Present and Future in the Treatment of Diabetic Kidney Disease. Journal of Diabetes Research. 2015. Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1068004
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1068004