Estrogen: An Emerging Regulator of Insulin Action and Mitochondrial Function
Joint Authors
Gupte, Anisha A.
Pownall, Henry J.
Hamilton, Dale J.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-26
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Clinical trials and animal studies have revealed that loss of circulating estrogen induces rapid changes in whole body metabolism, fat distribution, and insulin action.
The metabolic effects of estrogen are mediated primarily by its receptor, estrogen receptor-α; however, the detailed understanding of its mechanisms is incomplete.
Recent investigations suggest that estrogen receptor-α elicits the metabolic effects of estrogen by genomic, nongenomic, and mitochondrial mechanisms that regulate insulin signaling, substrate oxidation, and energetics.
This paper reviews clinical and experimental studies on the mechanisms of estrogen and the current state of knowledge regarding physiological and pathobiological influences of estrogen on metabolism.
American Psychological Association (APA)
Gupte, Anisha A.& Pownall, Henry J.& Hamilton, Dale J.. 2015. Estrogen: An Emerging Regulator of Insulin Action and Mitochondrial Function. Journal of Diabetes Research،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1068026
Modern Language Association (MLA)
Gupte, Anisha A.…[et al.]. Estrogen: An Emerging Regulator of Insulin Action and Mitochondrial Function. Journal of Diabetes Research No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1068026
American Medical Association (AMA)
Gupte, Anisha A.& Pownall, Henry J.& Hamilton, Dale J.. Estrogen: An Emerging Regulator of Insulin Action and Mitochondrial Function. Journal of Diabetes Research. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1068026
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1068026