Potential Renoprotective Agents through Inhibiting CTGFCCN2 in Diabetic Nephropathy

Joint Authors

Miao, Lining
Cui, Wenpeng
Wang, Songyan
Li, Bing
Li, Chunguang

Source

Journal of Diabetes Research

Issue

Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-11, 11 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2015-09-02

Country of Publication

Egypt

No. of Pages

11

Main Subjects

Diseases
Medicine

Abstract EN

Diabetic nephropathy (DN) is the leading cause of end-stage renal disease (ESRD).

The development and progression of DN might involve multiple factors.

Connective tissue growth factor (CCN2, originally known as CTGF) is the one which plays a pivotal role.

Therefore, increasing attention is being paid to CCN2 as a potential therapeutic target for DN.

Up to date, there are also many drugs or agents which have been shown for their protective effects against DN via different mechanisms.

In this review, we only focus on the potential renoprotective therapeutic agents which can specifically abolish CCN2 expression or nonspecifically inhibit CCN2 expression for retarding the development and progression of DN.

American Psychological Association (APA)

Wang, Songyan& Li, Bing& Li, Chunguang& Cui, Wenpeng& Miao, Lining. 2015. Potential Renoprotective Agents through Inhibiting CTGFCCN2 in Diabetic Nephropathy. Journal of Diabetes Research،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1068040

Modern Language Association (MLA)

Wang, Songyan…[et al.]. Potential Renoprotective Agents through Inhibiting CTGFCCN2 in Diabetic Nephropathy. Journal of Diabetes Research No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1068040

American Medical Association (AMA)

Wang, Songyan& Li, Bing& Li, Chunguang& Cui, Wenpeng& Miao, Lining. Potential Renoprotective Agents through Inhibiting CTGFCCN2 in Diabetic Nephropathy. Journal of Diabetes Research. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1068040

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1068040