Organic Compounds Detected in Deciduous Teeth: A Replication Study from Children with Autism in Two Samples
Joint Authors
Palmer, Raymond F.
Heilbrun, Lynne
Camann, David
Yau, Alice
Schultz, Stephen
Elisco, Viola
Tapia, Beatriz
Garza, Noe
Miller, Claudia
Source
Journal of Environmental and Public Health
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-07-29
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Biological samples are an important part of investigating toxic exposures and disease outcomes.
However, blood, urine, saliva, or hair can only reflect relatively recent exposures.
Alternatively, deciduous teeth have served as a biomarker of early developmental exposure to heavy metals, but little has been done to assess organic toxic exposures such as pesticides, plastics, or medications.
The purpose of our study was to determine if organic chemicals previously detected in a sample of typically developing children could be detected in teeth from a sample of children with autism.
Eighty-three deciduous teeth from children with autism spectrum disorders (ASD) were chosen from our tooth repository.
Organic compounds were assessed using liquid chromatography tandem mass spectrometry and gas chromatography methods.
Consistent with a prior report from Camann et al., (2013), we have demonstrated that specific semivolatile organic chemicals relevant to autism etiology can be detected in deciduous teeth.
This report provides evidence that teeth can be useful biomarkers of early life exposure for use in epidemiologic case-control studies seeking to identify differential unbiased exposures during development between those with and without specific disorders such as autism.
American Psychological Association (APA)
Palmer, Raymond F.& Heilbrun, Lynne& Camann, David& Yau, Alice& Schultz, Stephen& Elisco, Viola…[et al.]. 2015. Organic Compounds Detected in Deciduous Teeth: A Replication Study from Children with Autism in Two Samples. Journal of Environmental and Public Health،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1068205
Modern Language Association (MLA)
Palmer, Raymond F.…[et al.]. Organic Compounds Detected in Deciduous Teeth: A Replication Study from Children with Autism in Two Samples. Journal of Environmental and Public Health No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1068205
American Medical Association (AMA)
Palmer, Raymond F.& Heilbrun, Lynne& Camann, David& Yau, Alice& Schultz, Stephen& Elisco, Viola…[et al.]. Organic Compounds Detected in Deciduous Teeth: A Replication Study from Children with Autism in Two Samples. Journal of Environmental and Public Health. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1068205
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1068205