The Role of Intestinal Microbiota in Acute Graft-versus-Host Disease

Joint Authors

Chen, Yuanyuan
Zhao, Ye
Cheng, Qiao
Wu, Depei
Liu, Haiyan

Source

Journal of Immunology Research

Issue

Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2015-05-18

Country of Publication

Egypt

No. of Pages

9

Main Subjects

Biology

Abstract EN

The mammalian intestinal microbiota is a complex ecosystem that plays an important role in host immune responses.

Recent studies have demonstrated that alterations in intestinal microbiota composition are linked to multiple inflammatory diseases in humans, including acute graft-versus-host disease (aGVHD).

aGVHD is one of the major obstacles in allogeneic hematopoietic stem cell transplantation (allo-HSCT), characterized by tissue damage in the gastrointestinal (GI) tract, liver, lung, and skin.

Here, we review the current understanding of the role of intestinal microbiota in the control of immune responses during aGVHD.

Additionally, the possibility of using probiotic strains for potential treatment or prevention of aGVHD will be discussed.

American Psychological Association (APA)

Chen, Yuanyuan& Zhao, Ye& Cheng, Qiao& Wu, Depei& Liu, Haiyan. 2015. The Role of Intestinal Microbiota in Acute Graft-versus-Host Disease. Journal of Immunology Research،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1068369

Modern Language Association (MLA)

Chen, Yuanyuan…[et al.]. The Role of Intestinal Microbiota in Acute Graft-versus-Host Disease. Journal of Immunology Research No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1068369

American Medical Association (AMA)

Chen, Yuanyuan& Zhao, Ye& Cheng, Qiao& Wu, Depei& Liu, Haiyan. The Role of Intestinal Microbiota in Acute Graft-versus-Host Disease. Journal of Immunology Research. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1068369

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1068369