Treatment of Bullous Systemic Lupus Erythematosus
Joint Authors
Duan, Lihua
Shi, Guixiu
Chen, Liying
Zhong, Shan
Wang, Ying
Huang, Yan
He, Yan
Chen, Jie
Source
Journal of Immunology Research
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-18
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Bullous systemic lupus erythematosus (BSLE) is an autoantibody-mediated vesiculobullous disease in patients with SLE.
Autoimmunity in BSLE is characterized by the presence of circulating anti-type VII collagen antibodies.
BSLE patients often present with multiple, tense, clear fluid-filled vesicles and bullae overlying erythematous edematous plaques.
Skin biopsy from BSLE patients shows subepidermal bullae with numerous neutrophils and only occasional eosinophils.
Furthermore, immunofluorescence examination showed linear deposition of lgG, lgA, C3, and C1q along the basement membrane zone.
BSLE patients with corticosteroids treatment constantly do not receive a marked improvement, while dapsone generally dramatically improved the skin condition.
Recently, it has been reported that quite a few cases of BSLE were successfully treated with other immune suppressive drugs.
Therefore, a comprehensive review of the treatment of BSLE would be beneficial to cure the disease.
American Psychological Association (APA)
Duan, Lihua& Chen, Liying& Zhong, Shan& Wang, Ying& Huang, Yan& He, Yan…[et al.]. 2015. Treatment of Bullous Systemic Lupus Erythematosus. Journal of Immunology Research،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1068381
Modern Language Association (MLA)
Duan, Lihua…[et al.]. Treatment of Bullous Systemic Lupus Erythematosus. Journal of Immunology Research No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1068381
American Medical Association (AMA)
Duan, Lihua& Chen, Liying& Zhong, Shan& Wang, Ying& Huang, Yan& He, Yan…[et al.]. Treatment of Bullous Systemic Lupus Erythematosus. Journal of Immunology Research. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1068381
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1068381