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In Vitro Selection of Cancer Cell-Specific Molecular Recognition Elements from Amino Acid Libraries
Joint Authors
Williams, Ryan M.
Sooter, Letha J.
Source
Journal of Immunology Research
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-09-07
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Differential cell systematic evolution of ligands by exponential enrichment (SELEX) is an in vitro selection method for obtaining molecular recognition elements (MREs) that specifically bind to individual cell types with high affinity.
MREs are selected from initial large libraries of different nucleic or amino acids.
This review outlines the construction of peptide and antibody fragment libraries as well as their different host types.
Common methods of selection are also reviewed.
Additionally, examples of cancer cell MREs are discussed, as well as their potential applications.
American Psychological Association (APA)
Williams, Ryan M.& Sooter, Letha J.. 2015. In Vitro Selection of Cancer Cell-Specific Molecular Recognition Elements from Amino Acid Libraries. Journal of Immunology Research،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1068393
Modern Language Association (MLA)
Williams, Ryan M.& Sooter, Letha J.. In Vitro Selection of Cancer Cell-Specific Molecular Recognition Elements from Amino Acid Libraries. Journal of Immunology Research No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1068393
American Medical Association (AMA)
Williams, Ryan M.& Sooter, Letha J.. In Vitro Selection of Cancer Cell-Specific Molecular Recognition Elements from Amino Acid Libraries. Journal of Immunology Research. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1068393
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1068393