Comparative Immune Response in Children and Adults with H. pylori Infection
Joint Authors
Rafieian-Kopaei, Mahmoud
Razavi, Alireza
Bagheri, Nader
Azadegan-Dehkordi, Fatemeh
Shirzad, Mahsa
Rahimian, Ghorbanali
Shirzad, Hedaytollah
Source
Journal of Immunology Research
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-01
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Helicobacter pylori (H.
pylori) infection is generally acquired during early childhood; therefore, the immune response which usually takes place at this age may influence or even determine susceptibility to the infection contributing to the clinical outcomes in adulthood.
Several cytokines including IL-6, IL-10, and TGF-β1 as well as Foxp3+ cell numbers have been shown to be higher; however, some other cytokines consisting of IL-1β, IL-17A, and IL-23 are lower in infected children than in infected adults.
Immune response to H.
pylori infection in children is predominant Treg instead of Th17 cell response.
These results indicate that immune system responses probably play a role in persistent H.
pylori infection.
Childhood H.
pylori infection is also associated with significantly lower levels of inflammation and ulceration compared with adults.
This review, therefore, aimed to provide critical findings of the available literature about comparative immune system in children and adults with H.
pylori infection.
American Psychological Association (APA)
Razavi, Alireza& Bagheri, Nader& Azadegan-Dehkordi, Fatemeh& Shirzad, Mahsa& Rahimian, Ghorbanali& Rafieian-Kopaei, Mahmoud…[et al.]. 2015. Comparative Immune Response in Children and Adults with H. pylori Infection. Journal of Immunology Research،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1068436
Modern Language Association (MLA)
Razavi, Alireza…[et al.]. Comparative Immune Response in Children and Adults with H. pylori Infection. Journal of Immunology Research No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1068436
American Medical Association (AMA)
Razavi, Alireza& Bagheri, Nader& Azadegan-Dehkordi, Fatemeh& Shirzad, Mahsa& Rahimian, Ghorbanali& Rafieian-Kopaei, Mahmoud…[et al.]. Comparative Immune Response in Children and Adults with H. pylori Infection. Journal of Immunology Research. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1068436
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1068436