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The Multifaceted Role of Commensal Microbiota in Homeostasis and Gastrointestinal Diseases
Joint Authors
Silva, Marcelo José Barbosa
Carneiro, Matheus Batista Heitor
dos Anjos Pultz, Brunna
Pereira Silva, Danielle
Lopes, Mateus Eustáquio de Moura
dos Santos, Liliane Martins
Source
Journal of Immunology Research
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-22
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
The gastrointestinal tract houses a complex and diverse community of microbes.
In recent years, an increased understanding of the importance of intestinal microbiota for human physiology has been gained.
In the steady state, commensal microorganisms have a symbiotic relationship with the host and possess critical and distinct functions, including directly influencing immunity.
This means that recognition of commensal antigens is necessary for the development of complete immune responses.
Therefore, the immune system must face the challenge of maintaining mucosal homeostasis while dealing with undue passage of commensal or pathogenic microbes, as well as the host nutritional status or drug use.
Disruption of this fine balance has been associated with the development of several intestinal inflammatory diseases.
In this review, we discuss the mechanisms involved in the modulation of host-microbe interactions and how the breakdown of this homeostatic association can lead to intestinal inflammation and pathology.
American Psychological Association (APA)
Silva, Marcelo José Barbosa& Carneiro, Matheus Batista Heitor& dos Anjos Pultz, Brunna& Pereira Silva, Danielle& Lopes, Mateus Eustáquio de Moura& dos Santos, Liliane Martins. 2015. The Multifaceted Role of Commensal Microbiota in Homeostasis and Gastrointestinal Diseases. Journal of Immunology Research،Vol. 2015, no. 2015, pp.1-14.
https://search.emarefa.net/detail/BIM-1068440
Modern Language Association (MLA)
Silva, Marcelo José Barbosa…[et al.]. The Multifaceted Role of Commensal Microbiota in Homeostasis and Gastrointestinal Diseases. Journal of Immunology Research No. 2015 (2015), pp.1-14.
https://search.emarefa.net/detail/BIM-1068440
American Medical Association (AMA)
Silva, Marcelo José Barbosa& Carneiro, Matheus Batista Heitor& dos Anjos Pultz, Brunna& Pereira Silva, Danielle& Lopes, Mateus Eustáquio de Moura& dos Santos, Liliane Martins. The Multifaceted Role of Commensal Microbiota in Homeostasis and Gastrointestinal Diseases. Journal of Immunology Research. 2015. Vol. 2015, no. 2015, pp.1-14.
https://search.emarefa.net/detail/BIM-1068440
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1068440