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Harnessing the Microbiome to Enhance Cancer Immunotherapy
Joint Authors
Nelson, Michelle H.
Diven, Marshall A.
Huff, Logan W.
Paulos, Chrystal M.
Source
Journal of Immunology Research
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-25
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
The microbiota plays a key role in regulating the innate and adaptive immune system.
Herein, we review the immunological aspects of the microbiota in tumor immunity in mice and man, with a focus on toll-like receptor (TLR) agonists, vaccines, checkpoint modulators, chemotherapy, and adoptive T cell transfer (ACT) therapies.
We propose innovative treatments that may safely harness the microbiota to enhance T cell-based therapies in cancer patients.
Finally, we highlight recent developments in tumor immunotherapy, particularly novel ways to modulate the microbiome and memory T cell responses to human malignancies.
American Psychological Association (APA)
Nelson, Michelle H.& Diven, Marshall A.& Huff, Logan W.& Paulos, Chrystal M.. 2015. Harnessing the Microbiome to Enhance Cancer Immunotherapy. Journal of Immunology Research،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1068455
Modern Language Association (MLA)
Nelson, Michelle H.…[et al.]. Harnessing the Microbiome to Enhance Cancer Immunotherapy. Journal of Immunology Research No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1068455
American Medical Association (AMA)
Nelson, Michelle H.& Diven, Marshall A.& Huff, Logan W.& Paulos, Chrystal M.. Harnessing the Microbiome to Enhance Cancer Immunotherapy. Journal of Immunology Research. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1068455
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1068455