![](/images/graphics-bg.png)
Interactions between Innate Immunity, Microbiota, and Probiotics
Joint Authors
Giorgetti, GianMarco
Brandimarte, Giovanni
Fabiocchi, Federica
Ricci, Salvatore
Flamini, Paolo
Sandri, Giancarlo
Trotta, Maria Cristina
Elisei, Walter
Penna, Antonio
Lecca, Piera Giuseppina
Picchio, Marcello
Tursi, Antonio
Source
Journal of Immunology Research
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-18
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The term “microbiota” means genetic inheritance associated with microbiota, which is about 100 times larger than the guest.
The tolerance of the resident bacterial flora is an important key element of immune cell function.
A key role in the interaction between the host and the microbiota is played by Paneth cell, which is able to synthesize and secrete proteins and antimicrobial peptides, such as α/β defensins, cathelicidin, 14 β-glycosidases, C-type lectins, and ribonuclease, in response to various stimuli.
Recent studies found probiotics able to preserve intestinal homeostasis by downmodulating the immune response and inducing the development of T regulatory cells.
Specific probiotic strain, as well as probiotic-driven metabolic products called “postbiotics,” has been recently recognized and it is able to influence innate immunity.
New therapeutic approaches based on probiotics are now available, and further treatments based on postbiotics will come in the future.
American Psychological Association (APA)
Giorgetti, GianMarco& Brandimarte, Giovanni& Fabiocchi, Federica& Ricci, Salvatore& Flamini, Paolo& Sandri, Giancarlo…[et al.]. 2015. Interactions between Innate Immunity, Microbiota, and Probiotics. Journal of Immunology Research،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1068498
Modern Language Association (MLA)
Giorgetti, GianMarco…[et al.]. Interactions between Innate Immunity, Microbiota, and Probiotics. Journal of Immunology Research No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1068498
American Medical Association (AMA)
Giorgetti, GianMarco& Brandimarte, Giovanni& Fabiocchi, Federica& Ricci, Salvatore& Flamini, Paolo& Sandri, Giancarlo…[et al.]. Interactions between Innate Immunity, Microbiota, and Probiotics. Journal of Immunology Research. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1068498
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1068498