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Administration of Bifidobacterium breve PS12929 and Lactobacillus salivarius PS12934, Two Strains Isolated from Human Milk, to Very Low and Extremely Low Birth Weight Preterm Infants: A Pilot Study
Joint Authors
Rodríguez, Juan Miguel
Moles, Laura
Escribano, Esperanza
de Andrés, Javier
Montes, María Teresa
Sáenz de Pipaón, Miguel
Espinosa-Martos, Irene
Jiménez, Esther
Source
Journal of Immunology Research
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-22
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
The preterm infant gut has been described as immature and colonized by an aberrant microbiota.
Therefore, the use of probiotics is an attractive practice in hospitals to try to reduce morbidity and mortality in this population.
The objective of this pilot study was to elucidate if administration of two probiotic strains isolated from human milk to preterm infants led to their presence in feces.
In addition, the evolution of a wide spectrum of immunological compounds, including the inflammatory biomarker calprotectin, in both blood and fecal samples was also assessed.
For this purpose, five preterm infants received two daily doses (~109 CFU) of a 1 : 1 mixture of Bifidobacterium breve PS12929 and Lactobacillus salivarius PS12934.
Bacterial growth was detected by culture-dependent techniques in all the fecal samples.
The phylum Firmicutes dominated in nearly all fecal samples while L.
salivarius PS12934 was detected in all the infants at numerous sample collection points and B.
breve PS12929 appeared in five fecal samples.
Finally, a noticeable decrease in the fecal calprotectin levels was observed along time.
American Psychological Association (APA)
Moles, Laura& Escribano, Esperanza& de Andrés, Javier& Montes, María Teresa& Rodríguez, Juan Miguel& Jiménez, Esther…[et al.]. 2015. Administration of Bifidobacterium breve PS12929 and Lactobacillus salivarius PS12934, Two Strains Isolated from Human Milk, to Very Low and Extremely Low Birth Weight Preterm Infants: A Pilot Study. Journal of Immunology Research،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1068513
Modern Language Association (MLA)
Moles, Laura…[et al.]. Administration of Bifidobacterium breve PS12929 and Lactobacillus salivarius PS12934, Two Strains Isolated from Human Milk, to Very Low and Extremely Low Birth Weight Preterm Infants: A Pilot Study. Journal of Immunology Research No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1068513
American Medical Association (AMA)
Moles, Laura& Escribano, Esperanza& de Andrés, Javier& Montes, María Teresa& Rodríguez, Juan Miguel& Jiménez, Esther…[et al.]. Administration of Bifidobacterium breve PS12929 and Lactobacillus salivarius PS12934, Two Strains Isolated from Human Milk, to Very Low and Extremely Low Birth Weight Preterm Infants: A Pilot Study. Journal of Immunology Research. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1068513
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1068513