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Cellular and Antibody Based Approaches for Pediatric Cancer Immunotherapy
Joint Authors
Huang, Michael
Krishnadas, Deepa K.
Lucas, Kenneth G.
Source
Journal of Immunology Research
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-26
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Progress in the use of traditional chemotherapy and radiation-based strategies for the treatment of pediatric malignancies has plateaued in the past decade, particularly for patients with relapsing or therapy refractory disease.
As a result, cellular and humoral immunotherapy approaches have been investigated for several childhood cancers.
Several monoclonal antibodies are now FDA approved and commercially available, some of which are currently considered standard of practice.
There are also several new cellular immunotherapy approaches under investigation, including chimeric antigen receptor (CAR) modified T cells, cancer vaccines and adjuvants, and natural killer (NK) cell therapies.
In this review, we will discuss previous studies on pediatric cancer immunotherapy and new approaches that are currently being investigated in clinical trials.
American Psychological Association (APA)
Huang, Michael& Krishnadas, Deepa K.& Lucas, Kenneth G.. 2015. Cellular and Antibody Based Approaches for Pediatric Cancer Immunotherapy. Journal of Immunology Research،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1068547
Modern Language Association (MLA)
Huang, Michael…[et al.]. Cellular and Antibody Based Approaches for Pediatric Cancer Immunotherapy. Journal of Immunology Research No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1068547
American Medical Association (AMA)
Huang, Michael& Krishnadas, Deepa K.& Lucas, Kenneth G.. Cellular and Antibody Based Approaches for Pediatric Cancer Immunotherapy. Journal of Immunology Research. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1068547
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1068547