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Human Leukocyte Antigen Diversity: A Southern African Perspective
Joint Authors
Tshabalala, Mqondisi
Mellet, Juanita
Pepper, Michael S.
Source
Journal of Immunology Research
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-12
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Despite the increasingly well-documented evidence of high genetic, ethnic, and linguistic diversity amongst African populations, there is limited data on human leukocyte antigen (HLA) diversity in these populations.
HLA is part of the host defense mechanism mediated through antigen presentation to effector cells of the immune system.
With the high disease burden in southern Africa, HLA diversity data is increasingly important in the design of population-specific vaccines and the improvement of transplantation therapeutic interventions.
This review highlights the paucity of HLA diversity data amongst southern African populations and defines a need for information of this kind.
This information will support disease association studies, provide guidance in vaccine design, and improve transplantation outcomes.
American Psychological Association (APA)
Tshabalala, Mqondisi& Mellet, Juanita& Pepper, Michael S.. 2015. Human Leukocyte Antigen Diversity: A Southern African Perspective. Journal of Immunology Research،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1068580
Modern Language Association (MLA)
Tshabalala, Mqondisi…[et al.]. Human Leukocyte Antigen Diversity: A Southern African Perspective. Journal of Immunology Research No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1068580
American Medical Association (AMA)
Tshabalala, Mqondisi& Mellet, Juanita& Pepper, Michael S.. Human Leukocyte Antigen Diversity: A Southern African Perspective. Journal of Immunology Research. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1068580
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1068580