Bone Loss Triggered by the Cytokine Network in Inflammatory Autoimmune Diseases
Joint Authors
Amarasekara, Dulshara Sachini
Yu, Jiyeon
Rho, Jaerang
Source
Journal of Immunology Research
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-04
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Bone remodeling is a lifelong process in vertebrates that relies on the correct balance between bone resorption by osteoclasts and bone formation by osteoblasts.
Bone loss and fracture risk are implicated in inflammatory autoimmune diseases such as rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel disease, and systemic lupus erythematosus.
The network of inflammatory cytokines produced during chronic inflammation induces an uncoupling of bone formation and resorption, resulting in significant bone loss in patients with inflammatory autoimmune diseases.
Here, we review and discuss the involvement of the inflammatory cytokine network in the pathophysiological aspects and the therapeutic advances in inflammatory autoimmune diseases.
American Psychological Association (APA)
Amarasekara, Dulshara Sachini& Yu, Jiyeon& Rho, Jaerang. 2015. Bone Loss Triggered by the Cytokine Network in Inflammatory Autoimmune Diseases. Journal of Immunology Research،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1068607
Modern Language Association (MLA)
Amarasekara, Dulshara Sachini…[et al.]. Bone Loss Triggered by the Cytokine Network in Inflammatory Autoimmune Diseases. Journal of Immunology Research No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1068607
American Medical Association (AMA)
Amarasekara, Dulshara Sachini& Yu, Jiyeon& Rho, Jaerang. Bone Loss Triggered by the Cytokine Network in Inflammatory Autoimmune Diseases. Journal of Immunology Research. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1068607
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1068607