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Viral Interference and Persistence in Mosquito-Borne Flaviviruses
Joint Authors
De Nova-Ocampo, Mónica
Salas-Benito, Juan Santiago
Source
Journal of Immunology Research
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-25
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Mosquito-borne flaviviruses are important pathogens for humans, and the detection of two or more flaviviruses cocirculating in the same geographic area has often been reported.
However, the epidemiological impact remains to be determined.
Mosquito-borne flaviviruses are primarily transmitted through Aedes and Culex mosquitoes; these viruses establish a life-long or persistent infection without apparent pathological effects.
This establishment requires a balance between virus replication and the antiviral host response.
Viral interference is a phenomenon whereby one virus inhibits the replication of other viruses, and this condition is frequently associated with persistent infections.
Viral interference and persistent infection are determined by several factors, such as defective interfering particles, competition for cellular factors required for translation/replication, and the host antiviral response.
The interaction between two flaviviruses typically results in viral interference, indicating that these viruses share common features during the replicative cycle in the vector.
The potential mechanisms involved in these processes are reviewed here.
American Psychological Association (APA)
Salas-Benito, Juan Santiago& De Nova-Ocampo, Mónica. 2015. Viral Interference and Persistence in Mosquito-Borne Flaviviruses. Journal of Immunology Research،Vol. 2015, no. 2015, pp.1-14.
https://search.emarefa.net/detail/BIM-1068627
Modern Language Association (MLA)
Salas-Benito, Juan Santiago& De Nova-Ocampo, Mónica. Viral Interference and Persistence in Mosquito-Borne Flaviviruses. Journal of Immunology Research No. 2015 (2015), pp.1-14.
https://search.emarefa.net/detail/BIM-1068627
American Medical Association (AMA)
Salas-Benito, Juan Santiago& De Nova-Ocampo, Mónica. Viral Interference and Persistence in Mosquito-Borne Flaviviruses. Journal of Immunology Research. 2015. Vol. 2015, no. 2015, pp.1-14.
https://search.emarefa.net/detail/BIM-1068627
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1068627